AGBL2 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL20564977	0.51	3/20
SCHEMBL30035128	0.51	3/20
SCHEMBL12698841	1.00	2/20
SCHEMBL12698842	1.00	2/20
SCHEMBL29135531	0.71	2/20
SCHEMBL27889652	0.69	2/20
SCHEMBL4530478	0.69	2/20
SCHEMBL29781576	0.69	2/20
SCHEMBL3928210	0.68	2/20
SCHEMBL25376066	0.65	2/20
Hydrochloric Acid (SCHEMBL28487392)	0.63	2/20
SCHEMBL15544538	0.62	2/20
SCHEMBL13250884	0.61	2/20
SCHEMBL25373773	0.61	2/20
SCHEMBL17653807	0.60	2/20
SCHEMBL16386043	0.59	2/20
SCHEMBL16240808	0.58	2/20
SCHEMBL2589616	0.56	2/20
SCHEMBL26199719	0.54	2/20
SCHEMBL27462826	0.53	2/20

Clinical trials — most relevant to AGBL2 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Pharmacogenomic Evaluation of Antihypertensive Responses	PHASE4	COMPLETED
Study to Understand the Genetics of the Acute Response to Metformin and Glipizide in Humans	PHASE1	COMPLETED
Screening of Lysosomal Storage Disorders Diseases in Minority Groups	nan	UNKNOWN
SRT in Comparison to ERT on Immune Aspects and Bone Involvement in Gaucher Disease	nan	UNKNOWN
Factors Involved in Asthma and Airway Inflammation	nan	COMPLETED
Celiac Disease Genomic Environmental Microbiome and Metabolomic Study	nan	RECRUITING
Epidemiological and Genetic Studies of Body Mass Index	nan	COMPLETED
Molecular Epidemiology of Essential Hypertension	nan	COMPLETED
Proteogenomic Monitoring and Assessment of Liver Transplant Recipients	nan	RECRUITING
Catalytic Antibodies to Predict Uninvasively Late Transplant Failure	nan	COMPLETED
Identification of Acute Intermittent Porphyria Modifying Genes	nan	RECRUITING
Role of ADA SNPs in Subjects With Relapsing Multiple Sclerosis (RMS)	nan	UNKNOWN
PCD New Gene Discovery	nan	COMPLETED
Markers and Mechanisms of Macrovascular Disease in IDDM	nan	COMPLETED
Family Studies in Primary Biliary Cirrhosis (PBC)	nan	UNKNOWN
Chromosome 5Q Gene Variants and Asthma-Related Traits	nan	COMPLETED
Molecular Genetics Study of Nasopharyngeal Carcinoma: Characterization of NCP Susceptibility Gene(s)	nan	COMPLETED
Genomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African-Americans Study (GENE-FORECAST)	nan	COMPLETED
The Etiology and Progression of Brain Tumors	nan	COMPLETED
Family Blood Pressure Program - GENOA	nan	COMPLETED
Family Blood Pressure Program - SAPPHIRe Network	nan	COMPLETED
Risk Factors for the Development of Celiac Disease in Genetically Predisposed Children	nan	UNKNOWN
Identification of Genes Predisposing to Atherosclerosis	nan	COMPLETED
The Genetic Characterization of Dementia	nan	COMPLETED
Biomarkers of Lichen Sclerosus	nan	UNKNOWN
Integrated Proteomic HPLC-ESI-MS Analysis of Salivary Peptides of Preterm Newborns: a Pilot Study	nan	COMPLETED
Genetic Studies of Lysosomal Storage Disorders	nan	ENROLLING_BY_INVITATION
Clotting Genetic Variants, Hormones, and Venous Thrombosis	nan	COMPLETED
Family Blood Pressure Program - HyperGEN	nan	COMPLETED
HYPOCHOL : A Genetically-based Strategy to Identify New Targets in Cholesterol Metabolism	nan	ACTIVE_NOT_RECRUITING

Related proteins — ESM-2 sequence neighbours (a AGBL2 binder may also engage these)

Protein	Name	Similarity
Q8CDK2	—	1.000	Q8CDK2 →
Q8NEM8	—	0.998	Q8NEM8 →
Q4R632	—	0.997	Q4R632 →
Q8CDP0	—	0.997	Q8CDP0 →
Q0P4M4	—	0.995	Q0P4M4 →
E1B9D8	—	0.993	E1B9D8 →
B0JZV4	—	0.993	B0JZV4 →
Q5R978	—	0.992	Q5R978 →
A6H8T7	—	0.992	A6H8T7 →
Q6EEF3	—	0.991	Q6EEF3 →
Q5TKR9	—	0.990	Q5TKR9 →
A2A3K4	—	0.989	A2A3K4 →
KAT6B	Histone acetyltransferase KAT6B	0.989	landscape →
Q8BZ21	—	0.989	Q8BZ21 →
MAP3K13	Mitogen-activated protein kinase kinase kinase 13	0.988	landscape →
Q92613	—	0.988	Q92613 →
Q6ZT98	—	0.988	Q6ZT98 →
Q68UT7	—	0.988	Q68UT7 →
E1C2V1	—	0.988	E1C2V1 →
Q80TF6	—	0.988	Q80TF6 →
Q6EMB2	—	0.988	Q6EMB2 →
Q1ECV4	—	0.988	Q1ECV4 →
Q63553	—	0.988	Q63553 →
Q3ULB5	—	0.988	Q3ULB5 →
Q5FWM1	—	0.988	Q5FWM1 →
A7MBB4	—	0.987	A7MBB4 →
Q99PI4	—	0.987	Q99PI4 →
PIKFYVE	1-phosphatidylinositol 3-phosphate 5-kinase	0.987	landscape →
Q1LYM3	—	0.987	Q1LYM3 →
F4JZ68	—	0.987	F4JZ68 →