Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.56 |
| ▸ | TOP2A | P11388 | 3/20 | 0.37 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Creatinine SCHEMBL27811809 | 0.96 | CRBN (0.52) | CRBNTOP2ATOP2BALDH1A1MAPT | |
| Creatinine SCHEMBL28491793 | 0.95 | CRBN (0.56) | CRBNTOP2ATOP2BALDH1A1MAPT | |
| Creatinine SCHEMBL7203535 | 0.95 | — | — | |
| Creatinine SCHEMBL16295 | 0.95 | — | — | |
| Creatinine SCHEMBL8809815 | 0.95 | CRBN (0.61) | CRBNTOP2ATOP2BALDH1A1MAPT | |
| Creatinine SCHEMBL288087 | 0.95 | CRBN (0.61) | CRBNTOP2ATOP2BALDH1A1MAPT | |
| Creatinine SCHEMBL3287858 | 0.94 | CRBN (0.50) | CRBNTOP2ATOP2BALDH1A1MAPT | |
| Creatinine SCHEMBL7735944 | 0.94 | CRBN (0.50) | CRBNTOP2ATOP2BALDH1A1MAPT | |
| Creatinine SCHEMBL8637084 | 0.93 | — | — | |
| Creatinine SCHEMBL6473476 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8231914-B2 | Antioxidant compositions and methods thereto | Mannatech Incorporated (US) | 2012-07-31 | — | — | US | disclosed |
| US-20110256248-A1 | Antioxidant Compositions and Methods Thereto | MANNATECH, INCORPORATED (US) | 2011-10-20 | — | — | US | disclosed |
| US-7999003-B2 | Analyzing; measuring degradation of fluorescent material; using mixture of flavonoids and vitamin e | MANNATECH, INCORPORATED (US) | 2011-08-16 | — | — | US | disclosed |
| US-20050048143-A1 | Antioxidant compositions and methods thereto | MANNATECH, INC. (US) | 2005-03-03 | — | — | US | disclosed |