Creatinine

Creatinine

SCHEMBL288087

CN1CC(=O)NC1=N.CN1CC(=O)NC1=N

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 2/20 0.61
TOP2A P11388 3/20 0.39
TOP2B Q02880 3/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPT P10636 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
GAA P10253 1/20 0.33
PTGS1 P23219 2/20 0.32
LMNA P02545 1/20 0.32
BRD4 O60885 1/20 0.32
CREBBP Q92793 1/20 0.32
CYP11B1 P15538 1/20 0.31
CYP11B2 P19099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Creatinine SCHEMBL7203535 1.00
Creatinine SCHEMBL16295 1.00
Creatinine SCHEMBL8809815 1.00 CRBN (0.61) CRBNTOP2ATOP2BALDH1A1MAPT
Creatinine SCHEMBL4332495 0.98
Creatinine SCHEMBL3514057 0.98
Creatinine SCHEMBL435006 0.98
Creatinine SCHEMBL6473476 0.98
Creatinine SCHEMBL8637084 0.98
Creatinine SCHEMBL21404081 0.98
Creatinine SCHEMBL2922002 0.98

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023089308-A1 METHODS FOR TREATING CANCER BICYCLETX LIMITED (GB) 2023-05-25 WO disclosed
CN-116019831-A Application of gold nanospheres in preparation of drugs for regulating trimethylamine oxide metabolic disorder 中国人民解放军陆军军医大学第一附属医院 2023-04-28 CN disclosed
WO-2023013167-A1 CREATININE RISK ESTIMATION DEVICE, CREATININE RISK ESTIMATION METHOD, AND PROGRAM 日清食品ホールディングス株式会社 2023-02-09 WO disclosed
EP-3312640-B1 METHODS FOR AMPLIFYING AND DETECTING PATHOGEN NUCLEIC ACID IN A WHOLE BLOOD SAMPLE T2 BIOSYSTEMS INC (US) 2021-08-04 EP disclosed
US-20210181281-A1 NMR SYSTEMS AND METHODS FOR THE RAPID DETECTION OF ANALYTES T2 BIOSYSTEMS, INC. 2021-06-17 US disclosed
EP-3602071-A2 METHODS FOR QUANTITATION OF INSULIN AND C-PEPTIDE Quest Diagnostics Investments LLC (US) 2020-02-05 EP disclosed
WO-2018183966-A9 METHODS FOR QUANTITATION OF INSULIN AND C-PEPTIDE QUEST DIAGNOSTICS INVESTMENTS LLC (US) 2020-01-23 WO disclosed
US-20190214145-A1 Method and systems for creating and screening patient metabolite profile to diagnose current medical condition, diagnose current treatment state and recommend new treatment regimen KUREK ITZHAK (US) 2019-07-11 US disclosed
CN-109669935-A Check data screening method, apparatus, equipment and storage medium 平安医疗健康管理股份有限公司 2019-04-23 CN disclosed
WO-2018183966-A2 METHODS FOR QUANTITATION OF INSULIN AND C-PEPTIDE QUEST DIAGNOSTICS INVESTMENTS LLC (US) 2018-10-04 WO disclosed
EP-1003906-A1 FLUORESCENT POLYMERIC SENSOR FOR THE DETECTION OF CREATININE Bayer Corporation (US) 2000-05-31 EP disclosed
WO-2000023074-A1 PHARMACEUTICAL COMPOSITION CONTAINING DECURSIN BINEX CO., LTD. (KR) 2000-04-27 WO disclosed
WO-1999007881-A1 FLUORESCENT POLYMERIC SENSOR FOR THE DETECTION OF CREATININE BAYER CORPORATION (US) 1999-02-18 WO disclosed
US-5700694-A Method to detect bone and other connective tissue disorders in humans and animals THE ROWETT RESEARCH INSTITUTE (GB) 1997-12-23 US disclosed
US-5700693-A DETECTING CONCENTRATION OF PYRIDINIUM CROSSLINKED COLLAGE THE ROWETT RESEARCH INSTITUTE (GB) 1997-12-23 US disclosed
US-5324731-A Method of inhibiting transformation of cells in which purine metabolic enzyme activity is elevated AMIRA, INC. (US) 1994-06-28 US disclosed
US-5045465-A Culturing flavobacterium, a-ketoglutaric acid, ammonium sulfate EASTMAN KODAK COMPANY (US) 1991-09-03 US disclosed
EP-0230449-A1 SENSOR HAVING ION-SELECTIVE ELECTRODES EOS TECHNOLOGY CORPORATION (US) 1987-08-05 EP disclosed
WO-1987000286-A1 SENSOR HAVING ION-SELECTIVE ELECTRODES ILEX CORPORATION (US) 1987-01-15 WO disclosed
US-4275164-A PRODUCTION OF CREATINE IMINOHYDROLASE EASTMAN KODAK COMPANY (US) 1981-06-23 US disclosed