Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SI | P14410 | 1/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.46 |
| ▸ | KDM6B | O15054 | 1/20 | 0.46 |
| ▸ | KDM5C | P41229 | 1/20 | 0.46 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid Diethyl Ester SCHEMBL27830938 | 0.95 | MGAM (0.55) | SMN1; SMN2MGAMGAASIMGAM2 | |
| SCHEMBL262913 | 0.95 | MGAM (0.55) | SMN1; SMN2MGAMGAASIMGAM2 | |
| SCHEMBL363334 | 0.95 | MGAM (0.55) | SMN1; SMN2MGAMGAASIMGAM2 | |
| Succinic Acid Diethyl Ester SCHEMBL27966388 | 0.95 | MGAM (0.55) | SMN1; SMN2MGAMGAASIMGAM2 | |
| Water SCHEMBL1110192 | 0.93 | MGAM (0.52) | SMN1; SMN2MGAMGAASIMGAM2 | |
| Hydrochloric Acid SCHEMBL1006465 | 0.93 | MGAM (0.52) | SMN1; SMN2MGAMGAASIMGAM2 | |
| SCHEMBL5014278 | 0.93 | MGAM (0.52) | SMN1; SMN2MGAMGAASIMGAM2 | |
| SCHEMBL10784546 | 0.93 | MGAM (0.52) | SMN1; SMN2MGAMGAASIMGAM2 | |
| SCHEMBL818402 | 0.93 | MGAM (0.52) | SMN1; SMN2MGAMGAASIMGAM2 | |
| Methyl Alcohol SCHEMBL2707570 | 0.93 | MGAM (0.52) | SMN1; SMN2MGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101690794-B | Antitumor medicament, preparation method and quality control method | JILIN DOUBLE STAR PHARMACEUTICAL CO LTD | 2011-06-22 | — | — | CN | claimed |
| CN-101690794-A | Antitumor medicament, preparation method and quality control method | JILIN DOUBLE STAR PHARMACEUTIC | 2010-04-07 | — | — | CN | claimed |
| CN-1973866-A | Quality control method for cold treating and cough relieving syrup | GUIZHOU YIBAI PHARMACEUTICAL (CN) | 2007-06-06 | — | — | CN | claimed |
| US-5346919-A | Produced from Zopfiella; fungicides | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1994-09-13 | — | — | US | claimed |
| US-4495358-A | Antibiotic pyrrolomycin E | MEIJI SEIKA KAISHA, LTD. (JP) | 1985-01-22 | — | — | US | claimed |
| CN-101851590-B | Recombinant yeast for producing quinines compound | UNIV XINJIANG | 2013-11-06 | — | — | CN | disclosed |
| US-8546366-B2 | Method for inhibition of tumor cell growth using (22R)-5α-lanosta-8,24-dien-3β,15α,21-triol | MACKAY MEMORIAL HOSPITAL (TW) | 2013-10-01 | — | — | US | disclosed |
| US-20120309732-A1 | METHOD FOR INHIBITION OF TUMOR CELL GROWTH USING (22R)-5alpha-LANOSTA-8,24-DIEN-3Beta,15alpha,21-TRIOL | MACKAY MEMORIAL HOSPITAL (TW) | 2012-12-06 | — | — | US | disclosed |
| US-7994158-B2 | Method for inhibiting tumor growth with dehydrosulphurenic acid extracted from Antrodia cinnamomea | MACKAY MEMORIAL HOSPITAL (TW) | 2011-08-09 | — | — | US | disclosed |
| CN-101690794-B | Antitumor medicament, preparation method and quality control method | JILIN DOUBLE STAR PHARMACEUTICAL CO LTD | 2011-06-22 | — | — | CN | disclosed |
| CN-101703524-B | Quality control method for leech and preparation containing leech | LUNAN PHARM GROUP CORP | 2011-01-12 | — | — | CN | disclosed |
| CN-101703524-A | Quality control method for leech and preparation containing leech | LUNAN PHARM GROUP CORP | 2010-05-12 | — | — | CN | disclosed |
| US-4018799-A | INTERMEDIATES FOR TOCOPHEROL | HOFFMANN-LA ROCHE INC. (US) | 1977-04-19 | — | — | US | disclosed |
| US-4018753-A | ADRENAL STIMULANTS | SHIONOGI & CO., LTD. (JA) | 1977-04-19 | — | — | US | disclosed |
| US-4003919-A | INTERMEDIATES FOR ALPHA-TOCOPHEROL | HOFFMANN-LA ROCHE INC. (US) | 1977-01-18 | — | — | US | disclosed |
| US-3988356-A | Novel haptenes and antigens | ROUSSEL-UCLAF (FR) | 1976-10-26 | — | — | US | disclosed |
| US-3978084-A | Synthesis of biotin | HOFFMANN-LA ROCHE INC. (US) | 1976-08-31 | — | — | US | disclosed |
| US-3947473-A | (6-HYDROXY-CHROMAN-2-YL) CARBOXYLIC ACID DERIVATIVES | HOFFMAN-LA ROCHE INC. (US) | 1976-03-30 | — | — | US | disclosed |
| US-3935254-A | 5C-PROSTEN-13-YNOIC ACIDS | CARLO ERBA S.P.A. (IT) | 1976-01-27 | — | — | US | disclosed |
| US-3932467-A | Process for the production of 2β-formyl 3α-protected hydroxy-5-oxocyclopentane-1α-heptanoic acids and esters corresponding | G. D. SEARLE & CO. (US) | 1976-01-13 | — | — | US | disclosed |