SCHEMBL818402

SCHEMBL818402

CCOC(=O)CCC(=O)O.[NaH]

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.52
GAA P10253 1/20 0.52
SI P14410 1/20 0.52
MGAM2 Q2M2H8 1/20 0.52
CYP1A2 P05177 1/20 0.52
EGLN1 Q9GZT9 2/20 0.48
KDM6B O15054 1/20 0.48
KDM5C P41229 1/20 0.48
PHF8 Q9UPP1 1/20 0.48
KDM2A Q9Y2K7 1/20 0.48
ALDH1A1 P00352 4/20 0.48
TRPA1 O75762 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.46
LMNA P02545 5/20 0.45
ALKBH5 Q6P6C2 1/20 0.45
SUCNR1 Q9BXA5 1/20 0.45
POLB P06746 1/20 0.44
TSHR P16473 1/20 0.44
FFAR3 O14843 1/20 0.43
HDAC3 O15379 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinic Acid Diethyl Ester SCHEMBL27966388 0.97 MGAM (0.55) MGAMGAASIMGAM2CYP1A2
SCHEMBL363334 0.97 MGAM (0.55) MGAMGAASIMGAM2CYP1A2
SCHEMBL262913 0.97 MGAM (0.55) MGAMGAASIMGAM2CYP1A2
Succinic Acid Diethyl Ester SCHEMBL27830938 0.97 MGAM (0.55) MGAMGAASIMGAM2CYP1A2
SCHEMBL10784546 0.95 MGAM (0.52) MGAMGAASIMGAM2CYP1A2
Hydrochloric Acid SCHEMBL1006465 0.95 MGAM (0.52) MGAMGAASIMGAM2CYP1A2
Methyl Alcohol SCHEMBL6759312 0.95 MGAM (0.52) MGAMGAASIMGAM2CYP1A2
Methyl Alcohol SCHEMBL2707570 0.95 MGAM (0.52) MGAMGAASIMGAM2CYP1A2
Water SCHEMBL1110192 0.95 MGAM (0.52) MGAMGAASIMGAM2CYP1A2
Bromide SCHEMBL15666439 0.95 MGAM (0.52) MGAMGAASIMGAM2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104558154-B A kind of method extracting human albumin from component IV-2 precipitates 深圳市卫光生物制品股份有限公司 2016-10-12 CN disclosed
EP-2733137-A1 Carboxylic acid recovery and methods related thereto Board Of Trustees Of Michigan State University (US) 2014-05-21 EP disclosed
EP-2507200-B1 CARBOXYLIC ACID RECOVERY AND METHODS RELATED THERETO UNIV MICHIGAN STATE (US) 2014-02-12 EP disclosed
US-8293935-B2 Carboxylic acid recovery and methods related thereto BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2012-10-23 US disclosed
EP-2507200-A1 CARBOXYLIC ACID RECOVERY AND METHODS RELATED THERETO Board Of Trustees Of Michigan State University (US) 2012-10-10 EP disclosed
US-20110275851-A1 CARBOXYLIC ACID RECOVERY AND METHODS RELATED THERETO BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY 2011-11-10 US disclosed
WO-2011069008-A1 CARBOXYLIC ACID RECOVERY AND METHODS RELATED THERETO BOARD OF TRUSTEES MICHIGAN STATE UNIVERSITY (US) 2011-06-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110275851-A1 CARBOXYLIC ACID RECOVERY AND METHODS RELATED THERETO HAO2, HAO1, CA7 MGAM 1325/4885GAA 738/4885SI 167/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.