Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUCA1 | P04066 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ENGASE | Q8NFI3 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | FAP | Q12884 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22977773 | 0.88 | FUCA1 (0.42) | FUCA1GLAENGASENPSR1KDM4E | |
| SCHEMBL30421032 | 0.87 | CA1 (0.47) | FUCA1GLAENGASEFAPDPP4 | |
| SCHEMBL17249606 | 0.84 | — | — | |
| SCHEMBL13809941 | 0.80 | CYP2C9 (0.38) | FUCA1GLANPSR1KDM4EMAPK1 | |
| SCHEMBL13809942 | 0.80 | CYP2C9 (0.38) | FUCA1GLANPSR1KDM4EMAPK1 | |
| SCHEMBL24133924 | 0.80 | FUCA1 (0.38) | FUCA1GLAENGASENPSR1KDM4E | |
| SCHEMBL24333746 | 0.79 | DPP4 (0.39) | FUCA1FAPDPP4PREPMTNR1A | |
| SCHEMBL1866565 | 0.79 | FUCA1 (0.40) | FUCA1GLAENGASENPSR1KDM4E | |
| SCHEMBL25608119 | 0.78 | FUCA1 (0.37) | FUCA1GLAENGASENPSR1KDM4E | |
| SCHEMBL10563256 | 0.77 | FUCA1 (0.51) | FUCA1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198583-A1 | BICYCLIC JAK INHIBITORS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2020-10-01 | — | — | WO | disclosed |