Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 11/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 16/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | BMP1 | P13497 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22483007 | 0.81 | HDAC8 (0.79) | HDAC8HDAC6HDAC2HDAC11HDAC3 | |
| SCHEMBL22482884 | 0.79 | HDAC6 (0.55) | HDAC8HDAC6HDAC2HDAC11HDAC3 | |
| SCHEMBL22482906 | 0.75 | HDAC6 (0.65) | HDAC8HDAC6HDAC2HDAC11HDAC3 | |
| SCHEMBL22482986 | 0.73 | HDAC8 (1.00) | HDAC8HDAC6HDAC2HDAC11HDAC3 | |
| SCHEMBL22482736 | 0.71 | HDAC6 (1.00) | HDAC8HDAC6HDAC2HDAC11HDAC3 | |
| SCHEMBL22482915 | 0.69 | HDAC6 (0.53) | HDAC8HDAC6HDAC2HDAC11HDAC3 | |
| SCHEMBL20847640 | 0.67 | HDAC6 (0.48) | HDAC8HDAC6HDAC2HDAC11HDAC3 | |
| SCHEMBL22482885 | 0.65 | HDAC6 (0.59) | HDAC8HDAC6HDAC2HDAC11HDAC3 | |
| SCHEMBL20847653 | 0.62 | HDAC8 (0.50) | HDAC8HDAC6HDAC11HDAC3CA2 | |
| SCHEMBL22909297 | 0.60 | HDAC6 (0.42) | HDAC8HDAC6HDAC2HDAC11HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020194272-A1 | HALOGENATED PHENYLSULFONAMIDE HYDROXAMIC ACID COMPOUNDS, COMPOSITIONS AND USES THEREOF AS SELECTIVE HDAC6 INHIBITORS | 2681603 ONTARIO INC. (CA) | 2020-10-01 | — | — | WO | disclosed |