Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 11/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 12/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.44 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24472755 | 0.78 | HDAC3 (0.57) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL12592142 | 0.77 | HDAC3 (0.71) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL24472710 | 0.76 | HDAC6 (0.55) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL23054865 | 0.74 | HDAC3 (0.75) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL18085923 | 0.74 | HDAC1 (0.68) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL13949851 | 0.74 | HDAC1 (0.79) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL13949775 | 0.74 | HDAC3 (0.65) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL16806926 | 0.73 | HDAC6 (0.54) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL16806678 | 0.73 | HDAC6 (0.51) | HDAC6HDAC3HDAC1HDAC8HDAC2 | |
| SCHEMBL16806654 | 0.73 | HDAC6 (0.51) | HDAC6HDAC3HDAC1HDAC8HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020194272-A1 | HALOGENATED PHENYLSULFONAMIDE HYDROXAMIC ACID COMPOUNDS, COMPOSITIONS AND USES THEREOF AS SELECTIVE HDAC6 INHIBITORS | 2681603 ONTARIO INC. (CA) | 2020-10-01 | — | — | WO | disclosed |