Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 14/20 | 0.76 |
| ▸ | HDAC2 | Q92769 | 11/20 | 0.76 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.76 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.76 |
| ▸ | NCOR2 | Q9Y618 | 4/20 | 0.76 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.64 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.64 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.60 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.56 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.53 |
| ▸ | BMP1 | P13497 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8285508 | 0.94 | HDAC1 (0.84) | HDAC1HDAC2HDAC8HDAC3NCOR2 | |
| SCHEMBL20952239 | 0.91 | HDAC1 (0.91) | HDAC1HDAC2HDAC8HDAC3NCOR2 | |
| SCHEMBL13965309 | 0.85 | HDAC1 (1.00) | HDAC1HDAC2HDAC8HDAC3NCOR2 | |
| SCHEMBL22439788 | 0.83 | HDAC1 (0.68) | HDAC1HDAC2HDAC8HDAC3NCOR2 | |
| SCHEMBL19478284 | 0.81 | HDAC1 (0.79) | HDAC1HDAC2HDAC8HDAC3NCOR2 | |
| SCHEMBL22450018 | 0.81 | HDAC1 (0.66) | HDAC1HDAC2HDAC8HDAC3NCOR2 | |
| SCHEMBL13965291 | 0.80 | HDAC1 (0.69) | HDAC1HDAC2HDAC8HDAC3NCOR2 | |
| SCHEMBL13783921 | 0.80 | HDAC1 (0.83) | HDAC1HDAC2HDAC8HDAC3NCOR2 | |
| SCHEMBL13965297 | 0.79 | HDAC1 (0.71) | HDAC1HDAC2HDAC8HDAC3NCOR2 | |
| SCHEMBL8285512 | 0.79 | HDAC1 (0.71) | HDAC1HDAC2HDAC8HDAC3NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020193431-A1 | NOVEL INHIBITORS OF HISTONE DEACETYLASE 10 | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2020-10-01 | — | — | WO | disclosed |