Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.39 |
| ▸ | PRKCG | P05129 | 2/20 | 0.39 |
| ▸ | PRKCB | P05771 | 2/20 | 0.39 |
| ▸ | PRKCA | P17252 | 2/20 | 0.39 |
| ▸ | PRKCH | P24723 | 2/20 | 0.39 |
| ▸ | PRKCI | P41743 | 2/20 | 0.39 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.39 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.39 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22482940 | 0.85 | ALDH1A1 (0.58) | ALDH1A1EPHX1TSHRCYP1A2ALOX5 | |
| SCHEMBL22482952 | 0.85 | ALDH1A1 (0.58) | ALDH1A1EPHX1TSHRCYP1A2ALOX5 | |
| SCHEMBL22484377 | 0.83 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL22484690 | 0.80 | ALDH1A1 (0.52) | ALDH1A1EPHX1CYP1A2ALOX5PPARG | |
| SCHEMBL22470028 | 0.80 | ALDH1A1 (0.52) | ALDH1A1EPHX1CYP1A2ALOX5PPARG | |
| SCHEMBL22484489 | 0.80 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL22470052 | 0.78 | ALDH1A1 (0.46) | ALDH1A1EPHX1CYP1A2ALOX5PPARG | |
| SCHEMBL22482947 | 0.78 | ALDH1A1 (0.46) | ALDH1A1EPHX1CYP1A2ALOX5PPARG | |
| SCHEMBL22484610 | 0.78 | ALDH1A1 (0.54) | ALDH1A1EPHX1TSHRCYP1A2ALOX5 | |
| SCHEMBL22483050 | 0.76 | ALDH1A1 (0.52) | ALDH1A1EPHX1CYP1A2ALOX5PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020193649-A1 | NEW THERAPEUTIC APPLICATION OF 1,2-DIOXOLANE-3,5-DISUBSTITUTED COMPOUNDS, AND METHOD FOR THE PRODUCTION THEREOF | Universite Paris-Saclay (FR) | 2020-10-01 | — | — | WO | disclosed |