Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22707737 | 0.88 | PRMT5 (0.35) | PRMT5WDR77 | |
| SCHEMBL24090908 | 0.85 | PRMT5 (0.38) | PRMT5WDR77 | |
| SCHEMBL24090742 | 0.85 | PRMT5 (0.35) | PRMT5WDR77 | |
| SCHEMBL24534261 | 0.85 | PRMT5 (0.33) | PRMT5WDR77 | |
| SCHEMBL21122965 | 0.84 | PRMT5 (0.34) | PRMT5WDR77 | |
| SCHEMBL24595461 | 0.80 | PRMT5 (0.37) | PRMT5WDR77 | |
| SCHEMBL19667605 | 0.80 | PRMT5 (0.38) | PRMT5WDR77 | |
| SCHEMBL22494864 | 0.79 | PRMT5 (0.35) | PRMT5WDR77 | |
| SCHEMBL24659092 | 0.79 | PRMT5 (0.35) | PRMT5WDR77 | |
| SCHEMBL24659488 | 0.79 | PRMT5 (0.36) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198323-A1 | PRMT5 INHIBITORS AND USES THEREOF | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2020-10-01 | — | — | WO | disclosed |