Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 2/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22490419 | 1.00 | SLC1A3 (0.42) | SLC1A3SLC1A2SLC1A1MEN1KMT2A | |
| SCHEMBL23867741 | 0.85 | SLC1A3 (0.40) | SLC1A3SLC1A2SLC1A1MEN1KMT2A | |
| SCHEMBL19043738 | 0.85 | MEN1 (0.40) | SLC1A3SLC1A2SLC1A1MEN1KMT2A | |
| SCHEMBL16177521 | 0.83 | SLC1A3 (0.41) | SLC1A3SLC1A2SLC1A1MEN1KMT2A | |
| SCHEMBL20756666 | 0.83 | SLC1A3 (0.38) | SLC1A3SLC1A2SLC1A1MEN1KMT2A | |
| SCHEMBL20743832 | 0.83 | RCE1 (0.41) | SLC1A3SLC1A2SLC1A1MEN1KMT2A | |
| SCHEMBL16176950 | 0.83 | RCE1 (0.41) | SLC1A3SLC1A2SLC1A1MEN1KMT2A | |
| SCHEMBL19760189 | 0.83 | RCE1 (0.41) | SLC1A3SLC1A2SLC1A1MEN1KMT2A | |
| SCHEMBL11577777 | 0.82 | SLC1A3 (0.45) | SLC1A3SLC1A2SLC1A1MEN1KMT2A | |
| SCHEMBL10507146 | 0.81 | SLC1A3 (0.45) | SLC1A3SLC1A2SLC1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230037322-A1 | Cytotoxic Actin-Targeting Compounds | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2023-02-09 | — | — | US | disclosed |
| US-20230037322-A1 | Cytotoxic Actin-Targeting Compounds | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2023-02-09 | — | — | US | disclosed |
| US-11369594-B2 | Cytotoxic actin-targeting compounds | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2022-06-28 | — | — | US | disclosed |
| US-20200306233-A1 | Cytotoxic Actin-Targeting Compounds | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2020-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230037322-A1 | Cytotoxic Actin-Targeting Compounds | ACTB, ACTR2, MYC | SLC1A3 4796/4885SLC1A2 4871/4885SLC1A1 4805/4885 |
| US-11369594-B2 | Cytotoxic actin-targeting compounds | ACTB, ACTR2, MYC | SLC1A3 4796/4885SLC1A2 4871/4885SLC1A1 4805/4885 |
| US-20200306233-A1 | Cytotoxic Actin-Targeting Compounds | ACTB, ACTR2, MYC | SLC1A3 4796/4885SLC1A2 4871/4885SLC1A1 4805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.