Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CCR3 | P51677 | 1/20 | 0.45 |
| ▸ | STS | P08842 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22773364 | 1.00 | NPY2R (0.55) | NPY2RMEN1KMT2ALMNAALOX12 | |
| SCHEMBL29734657 | 1.00 | NPY2R (0.55) | NPY2RMEN1KMT2ALMNAALOX12 | |
| SCHEMBL21381907 | 0.88 | NPY2R (0.59) | NPY2RMEN1KMT2ALMNAALOX12 | |
| SCHEMBL22773363 | 0.88 | NPY2R (0.59) | NPY2RMEN1KMT2ALMNAALOX12 | |
| SCHEMBL22773246 | 0.87 | MEN1 (0.60) | NPY2RMEN1KMT2AALDH1A1 | |
| SCHEMBL22491552 | 0.87 | MEN1 (0.60) | NPY2RMEN1KMT2AALDH1A1 | |
| SCHEMBL20602790 | 0.87 | KMT2A (0.56) | NPY2RMEN1KMT2A | |
| SCHEMBL30567975 | 0.86 | PDE4B (0.47) | NPY2RMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL22773307 | 0.86 | PDE4B (0.47) | NPY2RMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL22773351 | 0.85 | NPY2R (0.44) | NPY2RMEN1KMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3717477-A1 | NEW HETEROCYCLIC COMPOUNDS | H. Hoffnabb-La Roche Ag (CH) | 2020-10-07 | — | — | EP | disclosed |