Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | NPY2R | P49146 | 10/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22773246 | 1.00 | MEN1 (0.60) | MEN1KMT2ANPY2RALDH1A1GPR119 | |
| SCHEMBL20602790 | 0.95 | KMT2A (0.56) | MEN1KMT2ANPY2RGPR119KDM4E | |
| SCHEMBL239883 | 0.93 | NPY2R (0.65) | MEN1KMT2ANPY2RALDH1A1GPR119 | |
| SCHEMBL3655794 | 0.91 | NPY2R (0.58) | MEN1KMT2ANPY2RALDH1A1GPR119 | |
| SCHEMBL22773327 | 0.91 | GPR119 (0.55) | MEN1KMT2ANPY2RGPR119 | |
| SCHEMBL23848259 | 0.88 | MEN1 (0.51) | MEN1KMT2AGPR119 | |
| SCHEMBL9170860 | 0.88 | KMT2A (0.56) | MEN1KMT2AALDH1A1GPR119KDM4E | |
| SCHEMBL22773364 | 0.87 | NPY2R (0.55) | MEN1KMT2ANPY2RALDH1A1 | |
| SCHEMBL22491564 | 0.87 | NPY2R (0.55) | MEN1KMT2ANPY2RALDH1A1 | |
| SCHEMBL29734657 | 0.87 | NPY2R (0.55) | MEN1KMT2ANPY2RALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3717477-A1 | NEW HETEROCYCLIC COMPOUNDS | H. Hoffnabb-La Roche Ag (CH) | 2020-10-07 | — | — | EP | disclosed |