SCHEMBL2249164

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2252552	0.86	SYK (0.55)	SYKMEN1KMT2AAURKBINCENP
	SCHEMBL2253143	0.86	DHFR (0.39)	MRGPRX4SYKMEN1MAPTKMT2A
	SCHEMBL2950029	0.83	EGFR (0.44)	MRGPRX4KDM4EMEN1ALDH1A1LMNA
	SCHEMBL2946180	0.82	DHFR (0.48)	MRGPRX4KDM4EMEN1ALDH1A1LMNA
	SCHEMBL29963026	0.82	SYK (0.50)	MRGPRX4SYKLMNAGAAMAPT
	SCHEMBL1016955	0.82	SYK (0.50)	MRGPRX4SYKLMNAGAAMAPT
	SCHEMBL2950833	0.81	MAPT (0.52)	MRGPRX4KDM4EMEN1ALDH1A1LMNA
	SCHEMBL2949651	0.80	MRGPRX4 (0.42)	MRGPRX4KDM4EMEN1ALDH1A1LMNA
	SCHEMBL2255723	0.80	EGFR (0.47)	MRGPRX4
	SCHEMBL2952862	0.80	MAP4K4 (0.44)	MRGPRX4KDM4EMEN1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.