Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 4/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 4/20 | 0.41 |
| ▸ | KCNQ4 | P56696 | 3/20 | 0.41 |
| ▸ | KCNQ5 | Q9NR82 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.33 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22492040 | 1.00 | KCNQ3 (0.41) | KCNQ3KCNQ2KCNQ4KCNQ5POLB | |
| SCHEMBL22492042 | 1.00 | KCNQ3 (0.41) | KCNQ3KCNQ2KCNQ4KCNQ5POLB | |
| SCHEMBL22492099 | 0.86 | KCNQ3 (0.53) | KCNQ3KCNQ2KCNQ4KCNQ5POLB | |
| SCHEMBL22492105 | 0.86 | KCNQ3 (0.53) | KCNQ3KCNQ2KCNQ4KCNQ5POLB | |
| SCHEMBL22492104 | 0.86 | KCNQ3 (0.53) | KCNQ3KCNQ2KCNQ4KCNQ5POLB | |
| SCHEMBL22492067 | 0.77 | POLB (0.38) | KCNQ3KCNQ2KCNQ4KCNQ5POLB | |
| SCHEMBL21611532 | 0.77 | KCNQ3 (0.38) | KCNQ3KCNQ2KCNQ4KCNQ5POLB | |
| SCHEMBL21611533 | 0.77 | KCNQ3 (0.38) | KCNQ3KCNQ2KCNQ4KCNQ5POLB | |
| SCHEMBL21611529 | 0.77 | KCNQ3 (0.38) | KCNQ3KCNQ2KCNQ4KCNQ5POLB | |
| SCHEMBL22492068 | 0.77 | POLB (0.38) | KCNQ3KCNQ2KCNQ4KCNQ5POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3717482-A1 | NEW PIPERIDINYL DERIVATIVES AS INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 7 | Les Laboratoires Servier SAS (FR) | 2020-10-07 | — | — | EP | disclosed |