⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8781897 | 0.96 | — | — | |
| SCHEMBL691231 | 0.69 | MGLL (0.33) | — | |
| SCHEMBL2010672 | 0.69 | MGLL (0.33) | — | |
| SCHEMBL996580 | 0.65 | — | — | |
| SCHEMBL8954376 | 0.64 | F2 (0.30) | — | |
| SCHEMBL14589063 | 0.64 | — | — | |
| SCHEMBL442896 | 0.64 | — | — | |
| SCHEMBL5773126 | 0.64 | — | — | |
| SCHEMBL442895 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL6810610 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103242694-A | Low-odor environment-friendly nano pigment ink-jet ink composition | JETBEST CORP | 2013-08-14 | — | — | CN | claimed |
| CN-102617450-A | Polymer material stabilizer and preparation method thereof | UNIV YANTAI | 2012-08-01 | — | — | CN | claimed |
| US-20150336943-A1 | NOVEL BENZODIOXANE-PIPERIDINE DERIVATIVES AND THEIR THERAPEUTIC APPLICATIONS FOR TREATING NEUROPSYCHIATRIC DISORDERS | PIERRE FABRE MEDICAMENT (FR) | 2015-11-26 | — | — | US | disclosed |
| EP-2537845-B1 | 6H-DIBENZO[B,E]OXEPINE DERIVED NONSTEROIDAL MINERALOCORTICOID RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2014-03-19 | — | — | EP | disclosed |
| CN-103242694-A | Low-odor environment-friendly nano pigment ink-jet ink composition | JETBEST CORP | 2013-08-14 | — | — | CN | disclosed |
| EP-2537845-A1 | 6H-dibenzo[B,E]oxepine derived nonsteroidal mineralocorticoid receptor antagonists | Eli Lilly and Company (US) | 2012-12-26 | — | — | EP | disclosed |
| EP-2235007-B1 | 6H-DIBENZ0 [B, E] OXEPINE DERIVED NONSTEROIDAL MINERALOCORTICOID RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2012-10-31 | — | — | EP | disclosed |
| CN-102617450-A | Polymer material stabilizer and preparation method thereof | UNIV YANTAI | 2012-08-01 | — | — | CN | disclosed |
| US-7994164-B2 | Mineralocorticoid receptor antagonists and methods of use | ELI LILLY AND COMPANY (US) | 2011-08-09 | — | — | US | disclosed |
| EP-2235007-A1 | 6H-DIBENZ0 [B, E] OXEPINE DERIVED NONSTEROIDAL MINERALOCORTICOID RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009085584-A1 | 6H-DIBENZ0 [B, E] OXEPINE DERIVED NONSTEROIDAL MINERALOCORTICOID RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2009-07-09 | — | — | WO | disclosed |
| US-20090163472-A1 | MINERALOCORTICOID RECEPTOR ANTAGONISTS AND METHODS OF USE | ELI LILLY AND COMPANY | 2009-06-25 | — | — | US | disclosed |