Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CCR5 | P51681 | 7/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28434751 | 0.85 | MAPT (0.40) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL26248008 | 0.84 | MAPT (0.46) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL26247966 | 0.82 | MAPT (0.46) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL22492486 | 0.79 | MAPT (0.37) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL28441986 | 0.79 | POLB (0.31) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL22492502 | 0.78 | MAPT (0.40) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL22492599 | 0.77 | MAPT (0.36) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL22492713 | 0.77 | MAPT (0.46) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL22492522 | 0.76 | MAPT (0.38) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL22492547 | 0.76 | MAPT (0.45) | MAPTLMNAMEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3717453-A2 | CREATINE PRODRUGS, COMPOSITIONS AND METHODS OF USE THEREOF | Ultragenyx Pharmaceutical Inc. (US) | 2020-10-07 | — | — | EP | disclosed |