Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26247966 | 0.93 | MAPT (0.46) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL26248008 | 0.92 | MAPT (0.46) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL22492522 | 0.89 | MAPT (0.38) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL22492517 | 0.85 | MAPT (0.36) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL26247985 | 0.82 | MAPT (0.43) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL28441986 | 0.81 | POLB (0.31) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL22492413 | 0.80 | MAPT (0.45) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL22492463 | 0.78 | MAPT (0.43) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL22492488 | 0.77 | MAPT (0.43) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL22492626 | 0.75 | MAPT (0.52) | MAPTLMNAMEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111417620-A | Creatine prodrugs, compositions thereof, and methods of use | 奥特吉尼克斯制药公司 | 2020-07-14 | — | — | CN | disclosed |