SCHEMBL2249279

SCHEMBL2249279

C[Si](C)(O[Si](O[Si](C)(C)c1ccccc1)(O[Si](C)(C)c1ccccc1)c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
NR1H2 P55055 2/20 0.31
NR1H3 Q13133 2/20 0.31
CA4 P22748 1/20 0.31
MAPT P10636 1/20 0.31
MGAM O43451 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18094250 0.89 ESR1 (0.34) ESR1ESR2NR1H2NR1H3CA4
SCHEMBL9771063 0.88 ESR1 (0.59) ESR1ESR2NR1H2NR1H3CA4
SCHEMBL121414 0.87 ESR1 (0.42) ESR1ESR2NR1H2NR1H3CA4
SCHEMBL13621398 0.82 ESR1 (0.39) ESR1ESR2NR1H2NR1H3CA4
SCHEMBL18125 0.82 ESR1 (0.39) ESR1ESR2NR1H2NR1H3CA4
SCHEMBL339880 0.82 ESR1 (0.39) ESR1ESR2NR1H2NR1H3CA4
SCHEMBL2248044 0.82 ESR1 (0.39) ESR1ESR2NR1H2NR1H3CA4
SCHEMBL13621387 0.82 ESR1 (0.39) ESR1ESR2NR1H2NR1H3CA4
SCHEMBL11434022 0.80 ESR1 (0.38) ESR1ESR2NR1H2NR1H3CA4
SCHEMBL14649181 0.80 ESR1 (0.38) ESR1ESR2NR1H2NR1H3CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7999033-B2 Thermoconductive silicone elastomer, thermoconductive silicone elastomer composition and thermoconductive medium DOW CORNING TORAY COMPANY, LTD. (JP) 2011-08-16 US disclosed
EP-1791911-B9 THERMOCONDUCTIVE SILICONE ELASTOMER, THERMOCONDUCTIVE SILICONE ELASTOMER COMPOSITION AND THERMOCONDUCTIVE MEDIUM DOW CORNING TORAY CO LTD (JP) 2010-05-19 EP disclosed
US-20090275688-A1 Thermoconductive Silicone Elastomer, Thermoconductive Silicone Elastomer Composition And Thermoconductive Medium DOW CORNING TORAY COMPANY, LTD. (JP) 2009-11-05 US disclosed
EP-1928970-B1 THERMOCONDUCTIVE SILICONE ELASTOMER, THERMOCONDUCTIVE SILICONE ELASTOMER COMPOSITION AND THERMOCONDUCTIVE MEDIUM DOW CORNING TORAY CO LTD (JP) 2009-10-28 EP disclosed
EP-1791911-B1 THERMOCONDUCTIVE SILICONE ELASTOMER, THERMOCONDUCTIVE SILICONE ELASTOMER COMPOSITION AND THERMOCONDUCTIVE MEDIUM DOW CORNING TORAY CO LTD (JP) 2009-09-30 EP disclosed
US-20090191414-A1 Thermoconductive Silicone Elastomer, Thermoconductive Silicone Elastomer Composition and Thermoconductive Medium DOW CORNING TORAY CO., LTD. (JP) 2009-07-30 US disclosed
EP-1928970-A1 THERMOCONDUCTIVE SILICONE ELASTOMER, THERMOCONDUCTIVE SILICONE ELASTOMER COMPOSITION AND THERMOCONDUCTIVE MEDIUM Dow Corning Toray Co., Ltd. (JP) 2008-06-11 EP disclosed
EP-1791911-A1 THERMOCONDUCTIVE SILICONE ELASTOMER, THERMOCONDUCTIVE SILICONE ELASTOMER COMPOSITION AND THERMOCONDUCTIVE MEDIUM Dow Corning Toray Co., Ltd. (JP) 2007-06-06 EP disclosed
WO-2007037019-A1 THERMOCONDUCTIVE SILICONE ELASTOMER, THERMOCONDUCTIVE SILICONE ELASTOMER COMPOSITION AND THERMOCONDUCTIVE MEDIUM DOW CORNING TORAY CO., LTD. (JP) 2007-04-05 WO disclosed
WO-2006025552-A1 THERMOCONDUCTIVE SILICONE ELASTOMER, THERMOCONDUCTIVE SILICONE ELASTOMER COMPOSITION AND THERMOCONDUCTIVE MEDIUM DOW CORNING TORAY CO., LTD. (JP) 2006-03-09 WO disclosed