SCHEMBL18125

SCHEMBL18125

C[Si](C)(C)O[Si](C)(C)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
NR1H2 P55055 2/20 0.32
NR1H3 Q13133 2/20 0.32
CA4 P22748 1/20 0.32
MAPT P10636 1/20 0.31
LMNA P02545 1/20 0.30
TSHR P16473 1/20 0.30
ALOX12 P18054 1/20 0.30
ACHE P22303 1/20 0.30
GPR3 P46089 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL121414 0.89 ESR1 (0.42) ESR1ESR2NR1H2NR1H3CA4
SCHEMBL1696199 0.88 ESR1 (0.35) ESR1ESR2
SCHEMBL15277333 0.88 ESR1 (0.35) ESR1ESR2
SCHEMBL2488828 0.86 ESR1 (0.34) ESR1ESR2
SCHEMBL18179380 0.86 ESR1 (0.34) ESR1ESR2
SCHEMBL30003086 0.84 ESR1 (0.33) ESR1ESR2
SCHEMBL2248044 0.84 ESR1 (0.39) ESR1ESR2NR1H2NR1H3CA4
SCHEMBL13621387 0.84 ESR1 (0.39) ESR1ESR2NR1H2NR1H3CA4
SCHEMBL13621398 0.84 ESR1 (0.39) ESR1ESR2NR1H2NR1H3CA4
SCHEMBL2249279 0.82 ESR1 (0.38) ESR1ESR2NR1H2NR1H3CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 472 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109776803-B Preparation method for regulating and controlling molecular weight and distribution of poly (dimethylsiloxane-co-methylvinylsiloxane) 中科院广州化学有限公司南雄材料生产基地 2021-07-23 CN claimed
CN-109776803-A A kind of poly- (dimethyl siloxane-co- methyl vinyl silicone) molecular weight of regulation and its preparation method of distribution 中科院广州化学有限公司南雄材料生产基地 2019-05-21 CN claimed
CN-107235996-A A kind of preparation method and application of trimethyl silicane alkoxide 壮铭新材料科技江苏有限公司 2017-10-10 CN claimed
CN-1592603-A Water-in-oil emulsion compositions comprising polyalkylene glycol styling agents PROCTER & GAMBLE (US) 2005-03-09 CN claimed
EP-1309306-A2 WATER-IN-OIL EMULSION COMPOSITIONS COMPRISING POLYALKYLENE GLYCOL STYLING AGENTS THE PROCTER & GAMBLE COMPANY (US) 2003-05-14 EP claimed
WO-2002011684-A2 WATER-IN-OIL EMULSION COMPOSITIONS COMPRISING POLYALKYLENE GLYCOL STYLING AGENTS THE PROCTER & GAMBLE COMPANY (US) 2002-02-14 WO claimed
US-6300027-B1 Low surface energy photoreceptors XEROX CORPORATION 2001-10-09 US claimed
JP-2001507372-A 2001-06-05 JP claimed
CN-1261776-A Personal care compositions containing grafted polymers PROCTER & GAMBLE (US) 2000-08-02 CN claimed
EP-0977540-A1 PERSONAL CARE COMPOSITIONS CONTAINING GRAFT POLYMERS THE PROCTER & GAMBLE COMPANY (US) 2000-02-09 EP claimed
WO-1998051261-A1 PERSONAL CARE COMPOSITIONS CONTAINING GRAFT POLYMERS THE PROCTER & GAMBLE COMPANY (US) 1998-11-19 WO claimed
EP-0333433-A2 Cosmetic and household products THE PROCTER & GAMBLE COMPANY (US) 1989-09-20 EP claimed
EP-4635577-A2 WATER-RESISTANT AND/OR PHOTOPROTECTIVE COMPOSITIONS COMPRISING NON-SOLUBILIZED MICRONIZED WAXES Lubrizol Advanced Materials, Inc. (US) 2025-10-22 EP disclosed
EP-4044992-B1 WATER-RESISTANT AND/OR PHOTOPROTECTIVE COMPOSITIONS COMPRISING NON-SOLUBILIZED MICRONIZED WAXES LUBRIZOL ADVANCED MAT INC (US) 2025-09-17 EP disclosed
US-20250000778-A1 CHELANT AND CYCLODEXTRIN COMPOSITIONS COTY INC. 2025-01-02 US disclosed
WO-2024228461-A1 ANTIBACTERIAL COMPOSITION 한국콜마주식회사 2024-11-07 WO disclosed
EP-0412704-A2 Hair conditioning and styling compositions THE PROCTER & GAMBLE COMPANY (US) 1991-02-13 EP disclosed
EP-0323715-A2 Hair styling agents and compositions containing the same THE PROCTER & GAMBLE COMPANY (US) 1989-07-12 EP disclosed
EP-0320218-A2 Low glass transition temperature adhesive copolymers for use in hair styling products THE PROCTER & GAMBLE COMPANY (US) 1989-06-14 EP disclosed
US-4247674-A Use of bis(fluoroaliphaticsulfonyl)imides in polymerization of organocyclosiloxanes MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1981-01-27 US disclosed