Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 9/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.72 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.72 |
| ▸ | PGR | P06401 | 5/20 | 0.72 |
| ▸ | TSHR | P16473 | 5/20 | 0.72 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.72 |
| ▸ | AR | P10275 | 4/20 | 0.72 |
| ▸ | MAPT | P10636 | 4/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.72 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.72 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.72 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.68 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.61 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.61 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.61 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.61 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.61 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16045649 | 0.92 | LMNA (0.75) | LMNACYP3A4NR3C1PGRTSHR | |
| SCHEMBL5664295 | 0.89 | LMNA (0.75) | LMNACYP3A4NR3C1PGRTSHR | |
| SCHEMBL5664622 | 0.89 | LMNA (0.75) | LMNACYP3A4NR3C1PGRTSHR | |
| SCHEMBL24102582 | 0.88 | LMNA (0.74) | LMNACYP3A4NR3C1PGRTSHR | |
| SCHEMBL6443765 | 0.88 | LMNA (0.74) | LMNACYP3A4NR3C1PGRTSHR | |
| SCHEMBL6442894 | 0.87 | CYP3A4 (0.80) | LMNACYP3A4NR3C1PGRTSHR | |
| SCHEMBL25863379 | 0.86 | LMNA (0.77) | LMNACYP3A4NR3C1PGRTSHR | |
| SCHEMBL25863374 | 0.86 | LMNA (0.77) | LMNACYP3A4NR3C1PGRTSHR | |
| SCHEMBL6445272 | 0.86 | LMNA (0.77) | LMNACYP3A4NR3C1PGRTSHR | |
| SCHEMBL6445511 | 0.86 | CYP3A4 (0.75) | LMNACYP3A4NR3C1PGRTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11752102-B2 | Powder preparation for nasal administration | ASKA PHARMACEUTICAL CO., LTD. (JP) | 2023-09-12 | — | — | US | disclosed |
| US-20220125716-A1 | POWDER PREPARATION FOR NASAL ADMINISTRATION | ASKA PHARMACEUTICAL CO., LTD. (JP) | 2022-04-28 | — | — | US | disclosed |
| US-11234928-B2 | Powder preparation for nasal administration | ASKA PHARMACEUTICAL CO., LTD. (JP) | 2022-02-01 | — | — | US | disclosed |
| US-20200360274-A1 | POWDER PREPARATION FOR NASAL ADMINISTRATION | ASKA PHARMACEUTICAL CO., LTD. (JP) | 2020-11-19 | — | — | US | disclosed |
| EP-3718550-A1 | POWDER PREPARATION FOR NASAL ADMINISTRATION | ASKA Pharmaceutical Co., Ltd. (JP) | 2020-10-07 | — | — | EP | disclosed |
| CN-111386119-A | Powder nasal administration preparation | ASKA制药株式会社 | 2020-07-07 | — | — | CN | disclosed |