⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22493066 | 0.90 | — | — | |
| SCHEMBL22493255 | 0.87 | CTSL (0.37) | — | |
| SCHEMBL22119342 | 0.84 | — | — | |
| SCHEMBL22493262 | 0.83 | — | — | |
| SCHEMBL32665827 | 0.78 | — | — | |
| SCHEMBL22245098 | 0.78 | — | — | |
| SCHEMBL22245117 | 0.77 | — | — | |
| SCHEMBL22119268 | 0.77 | — | — | |
| SCHEMBL29540271 | 0.77 | — | — | |
| SCHEMBL22493068 | 0.75 | GAA (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11001592-B2 | DNA polymerase IIIC inhibitors and use thereof | ACURX PHARMACEUTICALS, LLC (US) | 2021-05-11 | — | — | US | disclosed |
| US-20200308179-A1 | DNA Polymerase IIIC Inhibitors and Use Thereof | Acurx Pharmaceuticals, Inc. | 2020-10-01 | — | — | US | disclosed |