Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22481324 | 0.79 | MAPK8 (0.46) | KCNH2KDM4EALDH1A1 | |
| SCHEMBL22480852 | 0.78 | TRPV3 (0.38) | KCNH2CYP2D6CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL22493897 | 0.78 | TRPV3 (0.38) | KCNH2 | |
| SCHEMBL10841713 | 0.75 | F2 (0.44) | OPRM1KCNH2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9198043 | 0.75 | KCNH2 (0.44) | KCNH2CYP1A2MAPTCYP2C9CYP2C19 | |
| SCHEMBL17886911 | 0.73 | SMN1; SMN2 (0.46) | OPRM1KCNH2SMN1; SMN2ALDH1A1 | |
| SCHEMBL10653082 | 0.73 | KDM4E (0.44) | OPRM1MAPTSMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL14282017 | 0.73 | KCNH2 (0.50) | OPRM1KCNH2CYP1A2MAPTCYP2C9 | |
| SCHEMBL6856754 | 0.72 | KCNH2 (0.44) | KCNH2CYP1A2MAPTCYP2C9CYP2C19 | |
| SCHEMBL22493399 | 0.72 | CYP3A4 (0.36) | KCNH2CYP2D6MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024137506-A1 | COMPOSITIONS AND METHODS FOR IMPROVING NEUROLOGICAL DISEASES AND DISORDERS | CURASEN THERAPEUTICS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |
| WO-2020198466-A9 | BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME | CURASEN THERAPEUTICS, INC. (US) | 2020-12-30 | — | — | WO | disclosed |
| WO-2020198466-A1 | BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME | CURASEN THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |