Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 11/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 7/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 7/20 | 0.40 |
| ▸ | CDK1 | P06493 | 4/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATR | Q13535 | 1/20 | 0.40 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13529913 | 0.81 | DCK (0.47) | CDK2CCNA2CCNA1CDK1CCNB1 | |
| SCHEMBL13530549 | 0.80 | DCK (0.46) | CDK2CCNA2CCNA1CDK1CCNB1 | |
| SCHEMBL20772634 | 0.74 | CNR2 (0.34) | CDK2 | |
| SCHEMBL13530424 | 0.74 | DCK (0.48) | — | |
| SCHEMBL3248788 | 0.73 | CDK2 (0.48) | CDK2CCNA2CCNA1CDK1CCNB1 | |
| SCHEMBL1697615 | 0.72 | GAA (0.41) | CDK2CCNA2CCNA1CDK1CCNB1 | |
| SCHEMBL16294820 | 0.71 | MCHR1 (0.51) | CDK2CCNA2CCNA1CDK1CCNB1 | |
| SCHEMBL28275390 | 0.71 | CDK2 (0.42) | CDK2CCNA2CCNA1CDK1CCNB1 | |
| SCHEMBL3256222 | 0.70 | CDK2 (0.44) | CDK2CCNA2CCNA1CDK1CCNB1 | |
| SCHEMBL22235746 | 0.69 | CDK2 (0.46) | CDK2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200316064-A1 | CYCLIN-DEPENDENT KINASE 2 BIOMARKERS AND USES THEREOF | INCYTE CORPORATION | 2020-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200316064-A1 | CYCLIN-DEPENDENT KINASE 2 BIOMARKERS AND USES THEREOF | CDK2, CDK2AP2, CDKL2 | CDK2 1/4885CCNA2 8/4885CCNA1 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.