SCHEMBL22495531

SCHEMBL22495531

CCC(Sc1cc(-n2c(=O)[nH]c(C(F)(F)F)c(C)c2=O)c(F)cc1Cl)C(=O)O

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.31
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
DGAT1 O75907 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29527344 0.83 DGAT1 (0.32) POLBDGAT1
SCHEMBL22495447 0.83 DGAT1 (0.32) POLBDGAT1
SCHEMBL23135891 0.78 ITGB1 (0.31) POLBDGAT1
SCHEMBL22519870 0.76 PPARA (0.33)
SCHEMBL8903541 0.76 CCR1 (0.33) POLBALDH1A1DGAT1
SCHEMBL26420090 0.76
SCHEMBL22495520 0.76 POLB (0.32) POLBDGAT1
SCHEMBL29527219 0.76 POLB (0.32) POLBDGAT1
SCHEMBL22520062 0.76 POLB (0.32) POLB
SCHEMBL29527051 0.76 POLB (0.32) POLBDGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230131260-A1 SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS SYNGENTA CROP PROTECTION AG (CH) 2023-04-27 US disclosed
US-20200315174-A1 SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS SYNGENTA CROP PROTECTION AG (CH) 2020-10-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200315174-A1 SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS UNG, TYMP, TYMS POLB 758/4885ALDH1A1 170/4885GAA 514/4885
US-20230131260-A1 SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS UNG, TYMP, TYMS POLB 758/4885ALDH1A1 170/4885GAA 514/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.