Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 5/20 | 0.40 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | F2R | P25116 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FADS1 | O60427 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1767173 | 0.92 | PTGS1 (0.43) | PTGS1P2RX1RXFP1SMN1; SMN2NPC1 | |
| SCHEMBL1766487 | 0.92 | PTGS1 (0.43) | PTGS1P2RX1RXFP1NPC1RAB9A | |
| SCHEMBL31175820 | 0.88 | PTGS1 (0.40) | PTGS1P2RX1RXFP1SMN1; SMN2NPC1 | |
| SCHEMBL29549892 | 0.87 | PTGS1 (0.42) | PTGS1P2RX1RXFP1SMN1; SMN2NPC1 | |
| SCHEMBL1767085 | 0.87 | PTGS1 (0.42) | PTGS1P2RX1RXFP1SMN1; SMN2NPC1 | |
| SCHEMBL29615074 | 0.87 | PTGS1 (0.42) | PTGS1P2RX1RXFP1SMN1; SMN2CRBN | |
| SCHEMBL16155678 | 0.87 | FADS1 (0.40) | PTGS1P2RX1RXFP1SMN1; SMN2NPC1 | |
| SCHEMBL1766505 | 0.87 | PTGS1 (0.42) | PTGS1P2RX1RXFP1SMN1; SMN2CRBN | |
| SCHEMBL1766729 | 0.87 | PTGS1 (0.41) | PTGS1P2RX1RXFP1SMN1; SMN2KDM4E | |
| SCHEMBL29161215 | 0.86 | RXFP1 (0.40) | RXFP1SMN1; SMN2NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117342978-A | Cyanomethylation method of amine | 沈阳化工大学 | 2024-01-05 | — | — | CN | disclosed |
| WO-2021139370-A1 | AMIDE COMPOUND AND APPLICATION THEREOF | 沈阳化工大学 | 2021-07-15 | — | — | WO | disclosed |
| WO-2021139370-A1 | AMIDE COMPOUND AND APPLICATION THEREOF | 沈阳化工大学 | 2021-07-15 | — | — | WO | disclosed |
| WO-2021036966-A1 | BISAMIDE COMPOUND AND APPLICATION THEREOF | 沈阳化工大学 | 2021-03-04 | — | — | WO | disclosed |
| WO-2021036966-A1 | BISAMIDE COMPOUND AND APPLICATION THEREOF | 沈阳化工大学 | 2021-03-04 | — | — | WO | disclosed |
| WO-2021036965-A1 | ISOPHTHALAMIDE COMPOUND AND USE THEREOF | 沈阳化工大学 | 2021-03-04 | — | — | WO | disclosed |
| WO-2020200290-A1 | META-DIAMIDE COMPOUND AND APPLICATION THEREOF | 沈阳化工大学 | 2020-10-08 | — | — | WO | disclosed |