Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.36 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | F12 | P00748 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | NCF1 | P14598 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5623654 | 0.92 | ALDH1A1 (0.50) | ALDH1A1TSHRHSD17B10CYP3A4HPGD | |
| Hydrochloric Acid SCHEMBL5967545 | 0.90 | ALDH1A1 (0.48) | ALDH1A1TSHRHSD17B10CYP3A4HPGD | |
| SCHEMBL27976243 | 0.81 | MAPT (0.50) | ALDH1A1TSHRHSD17B10CYP3A4HPGD | |
| Pyrimidine SCHEMBL5624365 | 0.80 | ALDH1A1 (0.39) | ALDH1A1TSHRHSD17B10CYP3A4HPGD | |
| SCHEMBL358051 | 0.80 | ALDH1A1 (0.50) | ALDH1A1TSHRHSD17B10CYP3A4HPGD | |
| SCHEMBL1806270 | 0.76 | SLC2A1 (0.46) | ALDH1A1TSHRHSD17B10CYP3A4HPGD | |
| SCHEMBL31610446 | 0.76 | ALDH1A1 (0.42) | ALDH1A1TSHRHSD17B10CYP3A4HPGD | |
| SCHEMBL3635012 | 0.75 | CYP2A6 (0.58) | ALDH1A1TSHRHSD17B10CYP3A4HPGD | |
| SCHEMBL4688821 | 0.74 | ALDH1A1 (0.47) | ALDH1A1TSHRHSD17B10CYP3A4HPGD | |
| SCHEMBL23174989 | 0.72 | ALDH1A1 (0.42) | ALDH1A1TSHRHSD17B10CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113677680-B | EGFR inhibitor, composition and application thereof | 贝达药业股份有限公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-116891502-A | EGFR degrading agent | 上海齐鲁制药研究中心有限公司 | 2023-10-17 | — | — | CN | disclosed |
| CN-113166103-B | EGFR inhibitor and application thereof | 江苏先声药业有限公司 | 2022-12-16 | — | — | CN | disclosed |
| CN-113677680-A | EGFR inhibitor and composition and application thereof | 贝达药业股份有限公司 | 2021-11-19 | — | — | CN | disclosed |
| CN-113166103-A | EGFR inhibitor and application thereof | 江苏先声药业有限公司 | 2021-07-23 | — | — | CN | disclosed |
| WO-2020200191-A1 | EGFR INHIBITORS, COMPOSITIONS AND METHODS THERE OF | BETTA PHARMACEUTICALS CO., LTD (CN) | 2020-10-08 | — | — | WO | disclosed |