Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 1.00 |
| ▸ | ALK | Q9UM73 | 6/20 | 1.00 |
| ▸ | EML4 | Q9HC35 | 5/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22497626 | 0.88 | EGFR (0.85) | EGFRALKEML4 | |
| SCHEMBL22520213 | 0.88 | EGFR (1.00) | EGFRALKEML4 | |
| SCHEMBL22497656 | 0.88 | EGFR (1.00) | EGFRALKEML4 | |
| SCHEMBL19089663 | 0.88 | EGFR (0.82) | EGFRALKEML4 | |
| SCHEMBL19337095 | 0.87 | EGFR (0.77) | EGFRALKEML4 | |
| SCHEMBL19337136 | 0.87 | EGFR (0.77) | EGFRALKEML4 | |
| SCHEMBL22497633 | 0.87 | EGFR (0.77) | EGFRALKEML4 | |
| SCHEMBL19337177 | 0.87 | EGFR (0.76) | EGFRALKEML4 | |
| SCHEMBL19337163 | 0.87 | EGFR (0.76) | EGFRALKEML4 | |
| SCHEMBL27237904 | 0.87 | EGFR (0.80) | EGFRALKEML4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020200191-A1 | EGFR INHIBITORS, COMPOSITIONS AND METHODS THERE OF | BETTA PHARMACEUTICALS CO., LTD (CN) | 2020-10-08 | — | — | WO | disclosed |
| WO-2020200191-A1 | EGFR INHIBITORS, COMPOSITIONS AND METHODS THERE OF | BETTA PHARMACEUTICALS CO., LTD (CN) | 2020-10-08 | — | — | WO | disclosed |