SCHEMBL224977

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL227810	0.89	ESR1 (0.48)	ESR1ESR2SIGMAR1CA1CA2
	SCHEMBL227626	0.86	ESR1 (0.51)	ESR1ESR2CA1CA2ACHE
	SCHEMBL227894	0.86	ESR1 (0.47)	ESR1ESR2
	SCHEMBL224546	0.83	ESR1 (0.45)	ESR1ESR2CA1CA2ACHE
	SCHEMBL229164	0.82	ESR1 (0.49)	ESR1ESR2CA1CA2ACHE
	SCHEMBL225975	0.82	ESR1 (0.46)	ESR1ESR2CA1CA2ACHE
	SCHEMBL6426116	0.82	ESR1 (0.47)	ESR1ESR2CA1CA2ACHE
	SCHEMBL227627	0.82	ESR1 (0.53)	ESR1ESR2CA1CA2ACHE
	SCHEMBL226107	0.81	ESR1 (0.46)	ESR1ESR2CA1CA2ACHE
	SCHEMBL227703	0.81	ESR1 (0.66)	ESR1ESR2SIGMAR1DRD2DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.