Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1I | Q9P0X4 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29434491 | 1.00 | CACNA1I (0.39) | CACNA1ISMN1; SMN2MAPTKDM4EL3MBTL1 | |
| SCHEMBL22497918 | 0.83 | CACNA1I (0.44) | CACNA1ISMN1; SMN2MAPTKDM4EMAOB | |
| SCHEMBL29434470 | 0.83 | CACNA1I (0.44) | CACNA1ISMN1; SMN2MAPTKDM4EMAOB | |
| SCHEMBL24514026 | 0.81 | CACNA1I (0.46) | CACNA1ISMN1; SMN2MAPTKDM4EL3MBTL1 | |
| SCHEMBL22497917 | 0.81 | MAPT (0.38) | SMN1; SMN2MAPTKDM4EL3MBTL1MAOB | |
| SCHEMBL29434480 | 0.81 | MAPT (0.38) | SMN1; SMN2MAPTKDM4EL3MBTL1MAOB | |
| SCHEMBL22498000 | 0.77 | HDAC4 (0.37) | SMN1; SMN2MAPTKDM4EL3MBTL1NPC1 | |
| SCHEMBL29434492 | 0.77 | HDAC4 (0.37) | SMN1; SMN2MAPTKDM4EL3MBTL1NPC1 | |
| SCHEMBL22510361 | 0.74 | MAPT (0.33) | SMN1; SMN2MAPTKDM4EMAOBNPC1 | |
| SCHEMBL29659903 | 0.74 | MAPT (0.33) | SMN1; SMN2MAPTKDM4EMAOBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3947358-B1 | PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2025-06-18 | — | — | EP | disclosed |
| US-12281095-B2 | Pesticidally active diazine-amide compounds | SYNGENTA CROP PROTECTION AG (CH) | 2025-04-22 | — | — | US | disclosed |
| US-20220185789-A1 | PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2022-06-16 | — | — | US | disclosed |
| US-20220185789-A1 | PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2022-06-16 | — | — | US | disclosed |
| US-20220169629-A1 | PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2022-06-02 | — | — | US | disclosed |
| US-20220169629-A1 | PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2022-06-02 | — | — | US | disclosed |
| EP-3953343-A1 | PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS | Syngenta Crop Protection AG (CH) | 2022-02-16 | — | — | EP | disclosed |
| EP-3947358-A1 | PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS | Syngenta Crop Protection AG (CH) | 2022-02-09 | — | — | EP | disclosed |
| CN-113677672-A | Pesticidally active diazine-amide compounds | 先正达农作物保护股份公司 | 2021-11-19 | — | — | CN | disclosed |
| CN-113631549-A | Pesticidally active diazine-amide compounds | 先正达农作物保护股份公司 | 2021-11-09 | — | — | CN | disclosed |
| WO-2020208036-A1 | PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-10-15 | — | — | WO | disclosed |
| WO-2020208036-A1 | PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-10-15 | — | — | WO | disclosed |
| WO-2020201079-A1 | PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-10-08 | — | — | WO | disclosed |
| WO-2020201079-A1 | PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-10-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220185789-A1 | PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS | DDT, ACHE, NIT2 | CACNA1I 212/4885SMN1; SMN2 603/4885MAPT 674/4885 |
| US-12281095-B2 | Pesticidally active diazine-amide compounds | DDT, ACHE, NIT2 | CACNA1I 212/4885SMN1; SMN2 603/4885MAPT 674/4885 |
| US-20220169629-A1 | PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS | DDT, ACHE, NIT2 | CACNA1I 217/4885SMN1; SMN2 729/4885MAPT 569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.