Sugi Predict

Sugi Predict / Compounds / Guanosine

Guanosine

Guanosine

SCHEMBL22498413

CC(O)C(O)C(O)C(O)C=O.Nc1nc2c(ncn2[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]1.O=CC(O)C(O)C(O)C(O)CO

nearest known ligand 0.54

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Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ HPGD P15428 2/20 0.54
▸ HINT1 P49773 3/20 0.53
▸ NT5E P21589 1/20 0.51
▸ GSK3A P49840 2/20 0.48
▸ RPS6KA3 P51812 2/20 0.48
▸ MAPK14 Q16539 2/20 0.48
▸ TGM2 P21980 1/20 0.48
▸ TAAR1 Q96RJ0 1/20 0.48
▸ ADORA2A P29274 1/20 0.47
▸ ADORA2B P29275 1/20 0.47
▸ PNP P00491 1/20 0.47
▸ PAX8 Q06710 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Guanosine SCHEMBL22492949 0.96 HPGD (0.58) HPGDHINT1NT5EGSK3ARPS6KA3
Guanosine SCHEMBL22492951 0.96 HPGD (0.58) HPGDHINT1NT5EGSK3ARPS6KA3
Guanosine SCHEMBL22498410 0.96 HPGD (0.58) HPGDHINT1NT5EGSK3ARPS6KA3
Guanosine SCHEMBL22498408 0.96 HPGD (0.58) HPGDHINT1NT5EGSK3ARPS6KA3
Guanosine SCHEMBL11066196 0.96 HPGD (0.58) HPGDHINT1NT5EGSK3ARPS6KA3
Guanosine SCHEMBL19810339 0.94 HPGD (0.59) HPGDHINT1NT5EGSK3ARPS6KA3
Guanosine SCHEMBL3977221 0.94 HPGD (0.59) HPGDHINT1NT5EGSK3ARPS6KA3
Guanosine SCHEMBL19810340 0.94 HPGD (0.59) HPGDHINT1NT5EGSK3ARPS6KA3
Guanosine SCHEMBL22498411 0.93 HPGD (0.55) HPGDHINT1NT5EGSK3ARPS6KA3
Guanosine SCHEMBL28166235 0.93 HPGD (0.58) HPGDHINT1NT5EGSK3ARPS6KA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3784792-A1 ENZYMATIC METHOD FOR PREPARATION OF GDP-FUCOSE Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2021-03-03 — — EP claimed
WO-2020201315-A1 ENZYMATIC METHOD FOR PREPARATION OF GDP-FUCOSE MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2020-10-08 — — WO claimed
EP-3784792-A1 ENZYMATIC METHOD FOR PREPARATION OF GDP-FUCOSE Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2021-03-03 — — EP disclosed
WO-2020201315-A1 ENZYMATIC METHOD FOR PREPARATION OF GDP-FUCOSE MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2020-10-08 — — WO disclosed