Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10380003 | 0.73 | ALDH1A1 (0.52) | ALDH1A1TSHRSMN1; SMN2MAPTKMT2A | |
| SCHEMBL9298897 | 0.73 | — | — | |
| SCHEMBL17209851 | 0.73 | — | — | |
| SCHEMBL5612511 | 0.71 | ALDH1A1 (0.50) | ALDH1A1TSHRSMN1; SMN2MAPTKMT2A | |
| SCHEMBL30851 | 0.71 | — | — | |
| SCHEMBL3613613 | 0.69 | ALDH1A1 (0.42) | ALDH1A1TSHRSMN1; SMN2MAPTKMT2A | |
| Charcoal, Activated SCHEMBL890031 | 0.69 | — | — | |
| Ammonia Solution, Strong SCHEMBL1076016 | 0.69 | — | — | |
| SCHEMBL1506053 | 0.69 | ALDH1A1 (0.48) | ALDH1A1TSHRSMN1; SMN2MAPTKMT2A | |
| SCHEMBL9819151 | 0.69 | ALDH1A1 (0.62) | ALDH1A1TSHRSMN1; SMN2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6559167-B1 | Prodrugs of the pyridyl methyl sulfinyl benzimidazole type proton pump inhibitor drugs have a hydrolyzable arylsulfonyl or heteroarylsulfonyl group attached to the benzimidazole nitrogen. The prodrugs of the invention hydrolyze under | REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-05-06 | — | — | US | claimed |
| US-5278187-A | Cardioprotection drugs | BRITISH TECHNOLOGY GROUP LTD. (GB) | 1994-01-11 | — | — | US | claimed |
| US-5162372-A | Diester-diamide-diamine | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1992-11-10 | — | — | US | claimed |
| US-5149710-A | Pharmaceutical compositions for treating psoriasis | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1992-09-22 | — | — | US | claimed |
| US-4902714-A | N,N'-DIPROPARGYLOXYCARBONYLMETHYL-N,N'-DIAMINOCARBONYLMETHYL -1,2-DIAMINOPROPANE | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1990-02-20 | — | — | US | claimed |
| US-4755619-A | Pharmaceutical compositions | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1988-07-05 | — | — | US | claimed |
| EP-2760952-B1 | FLEXIBLE PAVEMENT MARKINGS | 3M INNOVATIVE PROPERTIES CO (US) | 2018-03-21 | — | — | EP | disclosed |
| EP-2760952-A1 | FLEXIBLE PAVEMENT MARKINGS | 3M Innovative Properties Company (US) | 2014-08-06 | — | — | EP | disclosed |
| US-20140213694-A1 | Flexible Pavement Markings | 3M IINOVATIVE PROPERTIES COMPANY (US) | 2014-07-31 | — | — | US | disclosed |
| WO-2013049488-A1 | FLEXIBLE PAVEMENT MARKINGS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-04-04 | — | — | WO | disclosed |
| US-20110177011-A1 | CERTAIN IMIDAZO[1,2-A]PYRAZIN-8-YLAMINES AND METHOD OF INHIBITION OF BRUTON'S TYROSINE KINASE BY SUCH COMPOUNDS | CURRIE KEVIN S | 2011-07-21 | — | — | US | disclosed |
| US-7405295-B2 | Certain imidazo[1,2-a]pyrazin-8-ylamines and method of inhibition of Bruton's tyrosine kinase by such compounds | CGI PHARMACEUTICALS, INC. (US) | 2008-07-29 | — | — | US | disclosed |
| WO-2007131881-A1 | Use of a high performance water vapor barrier coating for paper under tropical conditions | CIBA HOLDING INC. (CH) | 2007-11-22 | — | — | WO | disclosed |
| EP-0579469-A2 | N-acyldihydroquinoline derivatives as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-01-19 | — | — | EP | disclosed |
| US-5185025-A | SUBSTITUTED PYRAZOLES AND THEIR USE AS HERBICIDES | MONSANTO COMPANY (US) | 1993-02-09 | — | — | US | disclosed |
| US-5045106-A | 3-phenoxypyrazole | MONSANTO COMPANY (US) | 1991-09-03 | — | — | US | disclosed |
| US-4964895-A | Substituted 4-(4-nitrophenoxy) pyrazoles and their use as herbicides | MONSANTO COMPANY (US) | 1990-10-23 | — | — | US | disclosed |
| EP-0371947-A1 | Substituted pyrazoles and their use as herbicides | Monsanto Company (US) | 1990-06-06 | — | — | EP | disclosed |
| EP-0370990-A1 | Herbicidal substituted pyrazoles | MONSANTO COMPANY (US) | 1990-05-30 | — | — | EP | disclosed |
| EP-0295233-A2 | Substituted 3-(4-nitrophenoxy)pyrazoles and their use as herbicides | Monsanto Company (US) | 1988-12-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110177011-A1 | CERTAIN IMIDAZO[1,2-A]PYRAZIN-8-YLAMINES AND METHOD OF INHIBITION OF BRUTON'S TYROSINE KINASE BY SUCH COMPOUNDS | BTK, SYK, JAK1 | ALDH1A1 2736/4885TSHR 726/4885SMN1; SMN2 1641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.