Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 5/20 | 0.39 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PDE1A | P54750 | 1/20 | 0.34 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.34 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23114391 | 0.90 | PRMT5 (0.38) | PRMT5MBOAT4PDE1APDE1BPDE1C | |
| SCHEMBL15805581 | 0.88 | MBOAT4 (0.43) | MBOAT4HRH3KDM4EGLAHTT | |
| SCHEMBL22651671 | 0.87 | MBOAT4 (0.40) | PRMT5MBOAT4KCNH2HRH3 | |
| SCHEMBL20847695 | 0.84 | KDM4E (0.47) | MBOAT4HRH3KDM4EGLAHTT | |
| SCHEMBL24501504 | 0.84 | KDM4E (0.44) | MBOAT4HRH3KDM4EGLAHTT | |
| SCHEMBL29515354 | 0.83 | PRMT5 (0.41) | PRMT5MBOAT4KCNH2HRH3KDM4E | |
| SCHEMBL24323890 | 0.83 | PRMT5 (0.41) | PRMT5MBOAT4KCNH2HRH3KDM4E | |
| SCHEMBL20411982 | 0.80 | MBOAT4 (0.39) | MBOAT4KDM4EGLAHTTKMT2A | |
| SCHEMBL11919150 | 0.80 | TLR9 (0.46) | — | |
| SCHEMBL13179144 | 0.80 | MBOAT4 (0.39) | MBOAT4KDM4EGLAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10793604-B2 | Anthelmintic depsipeptide compounds | Boehringer Ingelheim Animal Health USA Inc. (US) | 2020-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10793604-B2 | Anthelmintic depsipeptide compounds | VIP, PREP, DNPEP | PRMT5 998/4885MBOAT4 3796/4885KCNH2 2864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.