SCHEMBL22503134

SCHEMBL22503134

O=C(Nc1ccccc1)NS(=O)(=O)C(F)(F)F

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACP1 P24666 2/20 0.62
SMN1; SMN2 Q16637 2/20 0.55
TP53 P04637 1/20 0.55
EPHX1 P07099 1/20 0.55
TSHR P16473 1/20 0.55
EPHX2 P34913 1/20 0.55
CDK9 P50750 1/20 0.55
CLK4 Q9HAZ1 1/20 0.55
LMNA P02545 1/20 0.51
KMT2A Q03164 4/20 0.50
MEN1 O00255 2/20 0.50
RAB9A P51151 2/20 0.50
MAPT P10636 2/20 0.50
HTT P42858 1/20 0.50
CA12 O43570 3/20 0.49
CA1 P00915 3/20 0.49
CA2 P00918 3/20 0.49
CA9 Q16790 3/20 0.49
CASP3 P42574 1/20 0.48
SENP7 Q9BQF6 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6468784 0.81 SAE1 (0.47) ACP1SMN1; SMN2TSHREPHX2LMNA
SCHEMBL31395420 0.79 ACP1 (0.69) ACP1SMN1; SMN2TP53EPHX1TSHR
SCHEMBL4421237 0.79 ACP1 (0.69) ACP1SMN1; SMN2TP53EPHX1TSHR
SCHEMBL8318477 0.79 ACP1 (0.74) ACP1SMN1; SMN2TP53EPHX1TSHR
Diphenylurea SCHEMBL11884167 0.77 SMN1; SMN2 (0.77) ACP1SMN1; SMN2TP53EPHX1TSHR
SCHEMBL6883439 0.76 PTPN1 (0.39) ACP1SMN1; SMN2KMT2AMEN1RAB9A
SCHEMBL24713108 0.76 ACP1 (0.69) ACP1SMN1; SMN2TP53EPHX1TSHR
SCHEMBL27832586 0.76 ACP1 (0.69) ACP1SMN1; SMN2TP53EPHX1TSHR
SCHEMBL4202296 0.76 ACP1 (0.69) ACP1SMN1; SMN2TP53EPHX1TSHR
SCHEMBL22503253 0.75 CA12 (0.46) LMNAKMT2AMEN1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230161252-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-25 US disclosed
US-10792489-B2 Bio-electrode composition, bio-electrode, and method for manufacturing the bio-electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-10-06 US disclosed