Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 4/20 | 0.46 |
| ▸ | MC3R | P41968 | 2/20 | 0.46 |
| ▸ | MC1R | Q01726 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 3/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | MC5R | P33032 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6367722 | 1.00 | CTSC (0.55) | CTSCALDH1A1MMECTSKKCNH2 | |
| SCHEMBL7971253 | 0.96 | CTSC (0.58) | CTSCALDH1A1MMECTSKKCNH2 | |
| SCHEMBL6374204 | 0.94 | CTSC (0.50) | CTSCALDH1A1MMECTSKKCNH2 | |
| SCHEMBL22127884 | 0.89 | CTSC (0.56) | CTSCMMECTSKKCNH2ACE | |
| SCHEMBL6367393 | 0.89 | CTSC (0.56) | CTSCMMECTSKKCNH2ACE | |
| SCHEMBL6367397 | 0.89 | CTSC (0.56) | CTSCMMECTSKKCNH2ACE | |
| SCHEMBL21808154 | 0.89 | CTSC (0.68) | CTSCALDH1A1MMECTSKKCNH2 | |
| SCHEMBL31026629 | 0.89 | CTSC (0.68) | CTSCALDH1A1MMECTSKKCNH2 | |
| SCHEMBL601567 | 0.89 | CTSC (0.68) | CTSCALDH1A1MMECTSKKCNH2 | |
| SCHEMBL28122660 | 0.89 | CTSC (0.68) | CTSCALDH1A1MMECTSKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210054025-A1 | ANTIMICROBIAL COMPOUNDS AND/OR MODULATORS OF MICROBIAL INFECTIONS AND METHODS OF USING THE SAME | UNIV INDIANA RES & TECH CORP (US) | 2021-02-25 | — | — | US | disclosed |
| US-10793594-B2 | Antimicrobial compounds and/or modulators of microbial infections and methods of using the same | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2020-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10793594-B2 | Antimicrobial compounds and/or modulators of microbial infections and methods of using the same | CD47, CGAS, FPR1 | CTSC 797/4885ALDH1A1 1257/4885MME 150/4885 |
| US-20210054025-A1 | ANTIMICROBIAL COMPOUNDS AND/OR MODULATORS OF MICROBIAL INFECTIONS AND METHODS OF USING THE SAME | CD47, CGAS, FPR1 | CTSC 797/4885ALDH1A1 1257/4885MME 150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.