Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 2/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15001039 | 0.79 | ALDH1A1 (0.41) | ALDH1A1MAPTPIM1PIM2 | |
| SCHEMBL19130676 | 0.78 | MAPT (0.33) | MAPTTSHRCYP2A6NPC1RAB9A | |
| SCHEMBL18133641 | 0.76 | MAPT (0.32) | MAPTTSHRCYP2A6 | |
| SCHEMBL12279085 | 0.76 | MAPT (0.32) | MAPTTSHRCYP2A6 | |
| SCHEMBL18309097 | 0.75 | MAPT (0.44) | ALDH1A1MAPTTSHRKDM4EGAA | |
| SCHEMBL12269059 | 0.75 | MAPT (0.39) | ALDH1A1MAPTTSHRKDM4EGAA | |
| SCHEMBL4416724 | 0.75 | ALDH1A1 (0.52) | ALDH1A1MAPTKDM4ECYP2A6L3MBTL1 | |
| SCHEMBL4416716 | 0.75 | MAPT (0.44) | ALDH1A1MAPTTSHRKDM4EGAA | |
| SCHEMBL4416728 | 0.75 | CYP2A6 (0.33) | MAPTTSHRCYP2A6 | |
| SCHEMBL12269018 | 0.74 | ALDH1A1 (0.44) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020203594-A1 | FLUORENE DERIVATIVE AND USE THEREOF | 日産化学株式会社 | 2020-10-08 | — | — | WO | disclosed |