Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.56 |
| ▸ | SLC28A3 | Q9HAS3 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | PDE5A | O76074 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | HMGCR | P04035 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.48 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1315483 | 1.00 | AKR1B1 (0.56) | AKR1B1SLC28A3TDP1TMPRSS2USP2 | |
| SCHEMBL13456979 | 1.00 | AKR1B1 (0.56) | AKR1B1SLC28A3TDP1TMPRSS2USP2 | |
| SCHEMBL4416998 | 1.00 | AKR1B1 (0.56) | AKR1B1SLC28A3TDP1TMPRSS2USP2 | |
| SCHEMBL4620889 | 1.00 | AKR1B1 (0.56) | AKR1B1SLC28A3TDP1TMPRSS2USP2 | |
| SCHEMBL1263104 | 1.00 | AKR1B1 (0.56) | AKR1B1SLC28A3TDP1TMPRSS2USP2 | |
| SCHEMBL16906157 | 1.00 | AKR1B1 (0.56) | AKR1B1SLC28A3TDP1TMPRSS2USP2 | |
| SCHEMBL11986810 | 1.00 | AKR1B1 (0.56) | AKR1B1SLC28A3TDP1TMPRSS2USP2 | |
| SCHEMBL5664342 | 0.89 | EPHX2 (0.55) | AKR1B1SLC28A3TMPRSS2USP2PDE5A | |
| SCHEMBL11986813 | 0.89 | SLC28A3 (0.50) | AKR1B1SLC28A3TDP1MAPK1PTPN1 | |
| SCHEMBL28793347 | 0.89 | TMPRSS2 (0.52) | AKR1B1TMPRSS2USP2PDE5ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230320987-A1 | LIPID NANOPARTICLES AND LIPOSOMES | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2023-10-12 | — | — | US | disclosed |
| US-20200315998-A1 | COMPOSITION FOR IMPROVING INTESTINAL BARRIER FUNCTION | SUNTORY HOLDINGS LIMITED (JP) | 2020-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200315998-A1 | COMPOSITION FOR IMPROVING INTESTINAL BARRIER FUNCTION | FABP2, SLC10A2, VIP | AKR1B1 1240/4885SLC28A3 141/4885TDP1 4632/4885 |
| US-20230320987-A1 | LIPID NANOPARTICLES AND LIPOSOMES | PHOSPHO1, LIPA, PLIN3 | AKR1B1 4047/4885SLC28A3 1241/4885TDP1 4439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.