⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL41331 | 1.00 | — | — | |
| SCHEMBL18843393 | 1.00 | ALDH1A1 (0.37) | — | |
| SCHEMBL739326 | 1.00 | — | — | |
| SCHEMBL1360 | 1.00 | — | — | |
| Methane SCHEMBL28281172 | 0.96 | — | — | |
| Water SCHEMBL27580599 | 0.96 | — | — | |
| Bromide SCHEMBL2734598 | 0.96 | — | — | |
| SCHEMBL31371887 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL437742 | 0.96 | — | — | |
| Ammonia Solution, Strong SCHEMBL2255969 | 0.96 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060167244-A1 | Polymerisation inhibitor | A H MARKS & CO LIMITED (GB) | 2006-07-27 | — | — | US | claimed |
| EP-1511704-A1 | POLYMERISATION INHIBITOR | A H Marks & Company Limited (GB) | 2005-03-09 | — | — | EP | claimed |
| WO-2003106390-A1 | POLYMERISATION INHIBITOR | A H MARKS & COMPANY LIMITED (GB) | 2003-12-24 | — | — | WO | claimed |
| EP-4602020-A1 | ANTIPOLYMERANT COMPOSITIONS WITH NAPHTHOQUINONE AND HYDROXYLAMINE AND METHODS OF USING | Ecolab USA, Inc. (US) | 2025-08-20 | — | — | EP | disclosed |
| WO-2024081354-A1 | ANTIPOLYMERANT COMPOSITIONS WITH NAPHTHOQUINONE AND HYDROXYLAMINE AND METHODS OF USING | ECOLAB USA INC. (US) | 2024-04-18 | — | — | WO | disclosed |
| CN-115491151-A | Holographic pattern film and preparation process thereof | 东莞市光纳光电科技有限公司 | 2022-12-20 | — | — | CN | disclosed |
| EP-1889836-B1 | NOVEL PYRIDINE DERIVATIVE AND PYRIMIDINE DERIVATIVE (3) | EISAI R&D MAN CO LTD (JP) | 2013-06-12 | — | — | EP | disclosed |
| US-8288538-B2 | Pyridine derivatives and pyrimidine derivatives (3) | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-10-16 | — | — | US | disclosed |
| US-20120232049-A1 | PYRIDINE OR PYRIMIDINE DERIVATIVE HAVING EXCELLENT CELL GROWTH INHIBITION EFFECT AND EXCELLENT ANTI-TUMOR EFFECT ON CELL STRAIN HAVING AMPLIFICATION OF HGFR GENE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-09-13 | — | — | US | disclosed |
| US-7998948-B2 | Pharmaceutical composition for treating esophageal cancer | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-08-16 | — | — | US | disclosed |
| US-7855290-B2 | N-[4-({2-[({4-[2-(Dimethylamino)ethyl]piperazin-1-yl}carbonyl)amino]pyridin-4-yl}oxy)-2-fluorophenyl]-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide; hepatocyte growth factor receptor (HGFR) inhibitors; antitumor, -carcinogenic, -metastasis agents | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-12-21 | — | — | US | disclosed |
| US-20080319188-A1 | Novel pyridine derivatives and pyrimidine derivatives (3) | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2008-12-25 | — | — | US | disclosed |
| EP-1889836-A1 | NOVEL PYRIDINE DERIVATIVE AND PYRIMIDINE DERIVATIVE (3) | Eisai R&D Management Co., Ltd. (JP) | 2008-02-20 | — | — | EP | disclosed |
| US-20070270421-A1 | Novel pyridine Derivative and Pyrimidine Derivative (1) | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-11-22 | — | — | US | disclosed |
| EP-1719763-A1 | NOVEL PYRIDINE DERIVATIVE AND PYRIMIDINE DERIVATIVE (2) | Eisai Co., Ltd. (JP) | 2006-11-08 | — | — | EP | disclosed |
| EP-1719762-A1 | NOVEL PYRIDINE DERIVATIVE AND PYRIMIDINE DERIVATIVE (1) | Eisai Co., Ltd. (JP) | 2006-11-08 | — | — | EP | disclosed |
| US-20060167244-A1 | Polymerisation inhibitor | A H MARKS & CO LIMITED (GB) | 2006-07-27 | — | — | US | disclosed |
| US-20050277652-A1 | Novel pyridine derivative and pyrimidine derivative | EISAI CO., LTD. (JP) | 2005-12-15 | — | — | US | disclosed |
| EP-1511704-A1 | POLYMERISATION INHIBITOR | A H Marks & Company Limited (GB) | 2005-03-09 | — | — | EP | disclosed |
| WO-2003106390-A1 | POLYMERISATION INHIBITOR | A H MARKS & COMPANY LIMITED (GB) | 2003-12-24 | — | — | WO | disclosed |