Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22507428 | 0.94 | LMNA (0.46) | ESR1ESR2TP53MAPTHDAC1 | |
| SCHEMBL22513587 | 0.93 | TP53 (0.49) | ESR1ESR2TP53MAPTHDAC1 | |
| SCHEMBL22513621 | 0.91 | TP53 (0.52) | ESR1ESR2TP53MAPTHDAC1 | |
| SCHEMBL22513588 | 0.90 | RECQL (0.45) | ESR1ESR2TP53MAPTHDAC1 | |
| SCHEMBL22926671 | 0.89 | ESR1 (0.60) | ESR1ESR2TP53MAPTHDAC1 | |
| SCHEMBL22507313 | 0.89 | ESR2 (0.60) | ESR1ESR2HDAC1HDAC8HDAC6 | |
| SCHEMBL22513591 | 0.89 | ESR2 (0.60) | ESR1ESR2HDAC1HDAC8HDAC6 | |
| SCHEMBL22507340 | 0.88 | TP53 (0.52) | ESR1ESR2TP53MAPTHDAC1 | |
| SCHEMBL20776075 | 0.88 | ESR1 (0.58) | ESR1ESR2TP53MAPTHDAC1 | |
| SCHEMBL18308619 | 0.88 | ESR1 (0.58) | ESR1ESR2TP53MAPTHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020199996-A1 | SUBSTITUTED 1,3,5-TRIAZINE COMPOUND, COMPOSITION AND APPLICATION THEREOF | 吉林省元合电子材料有限公司 | 2020-10-08 | — | — | WO | disclosed |