Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12700643 | 0.89 | CSNK2A1 (0.35) | F2CSNK2A1L3MBTL1CSNK2A2 | |
| SCHEMBL22508171 | 0.89 | CSNK2A1 (0.39) | F2CSNK2A1L3MBTL1CSNK2A2 | |
| SCHEMBL22508201 | 0.83 | F2 (0.36) | F2CSNK2A1L3MBTL1 | |
| SCHEMBL12695835 | 0.79 | NR1I2 (0.38) | F2CSNK2A1L3MBTL1CSNK2A2 | |
| SCHEMBL22508203 | 0.77 | F2 (0.33) | F2 | |
| SCHEMBL25522772 | 0.76 | F2 (0.41) | F2CSNK2A1L3MBTL1CSNK2A2 | |
| SCHEMBL30179199 | 0.71 | DGAT1 (0.34) | L3MBTL1 | |
| SCHEMBL2800162 | 0.70 | AKT1 (0.39) | F2L3MBTL1 | |
| SCHEMBL89601 | 0.70 | GRIN2D (0.39) | L3MBTL1 | |
| SCHEMBL22957198 | 0.70 | PDK2 (0.37) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020205564-A1 | CYTOTOXIC BIS-BENZODIAZEPINE DERIVATIVES AND CONJUGATES THEREOF WITH CELL-BINDING AGENTS FOR INHIBITING ABNORMAL CELL GROWTH OR FOR TREATING PROLIFERATIVE DISEASES | IMMUNOGEN, INC. (US) | 2020-10-08 | — | — | WO | disclosed |