Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17A | Q9UEE5 | 10/20 | 0.70 |
| ▸ | STK17B | O94768 | 5/20 | 0.70 |
| ▸ | IGF1R | P08069 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | BCL6 | P41182 | 4/20 | 0.51 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20154824 | 0.83 | STK17A (1.00) | STK17ASTK17B | |
| SCHEMBL20154728 | 0.80 | STK17A (1.00) | STK17ASTK17B | |
| SCHEMBL21365160 | 0.79 | STK17A (0.67) | STK17ASTK17BGAA | |
| SCHEMBL22508341 | 0.78 | STK17A (0.76) | STK17ASTK17BMAPTMEN1LMNA | |
| SCHEMBL22508340 | 0.77 | STK17A (0.75) | STK17ASTK17B | |
| SCHEMBL21364913 | 0.76 | STK17A (0.88) | STK17ASTK17B | |
| SCHEMBL22508313 | 0.76 | STK17A (0.73) | STK17ASTK17BMAPTMEN1LMNA | |
| SCHEMBL22490561 | 0.75 | STK17A (0.76) | STK17ASTK17BMAPTNPC1RAB9A | |
| SCHEMBL17231255 | 0.74 | IGF1R (0.65) | IGF1RMAPTMEN1LMNAKMT2A | |
| SCHEMBL11935576 | 0.73 | STK17B (0.57) | STK17ASTK17BMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3539951-B1 | NOVEL PYRIMIDINE COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING CANCER AND INFLAMMATORY DISEASES | KOREA RES INST CHEMICAL TECH (KR) | 2020-10-07 | — | — | EP | disclosed |