Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18499505 | 0.77 | SLC22A12 (0.42) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL20417744 | 0.76 | PI4KA (0.43) | FGFR1PRMT5WDR77ALDH1A1MEN1 | |
| SCHEMBL1092832 | 0.76 | SLC22A12 (0.44) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19465328 | 0.76 | SLC22A12 (0.44) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29407694 | 0.76 | NOTUM (0.46) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL130757 | 0.76 | NOTUM (0.46) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL18572036 | 0.76 | SLC22A12 (0.48) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16769961 | 0.76 | SLC22A12 (0.41) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16254748 | 0.73 | SLC22A12 (0.42) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL22667781 | 0.73 | SLC22A12 (0.42) | SLC22A12PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020206308-A1 | SELECTIVE INHIBITORS OF PROTEIN ARGININE METHYLTRANSFERASE 5 | PRELUDE THERAPEUTICS, INCORPORATED (US) | 2020-10-08 | — | — | WO | disclosed |