Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCK1 | P16333 | 1/20 | 0.53 |
| ▸ | BACE1 | P56817 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.40 |
| ▸ | SLC14A1 | Q13336 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30908485 | 0.85 | NCK1 (0.48) | NCK1BACE1CYP1A2MEN1KMT2A | |
| SCHEMBL22509697 | 0.85 | NCK1 (0.48) | NCK1BACE1CYP1A2MEN1KMT2A | |
| SCHEMBL4864428 | 0.80 | NCK1 (0.57) | NCK1BACE1CYP1A2MEN1KMT2A | |
| SCHEMBL14702032 | 0.80 | NCK1 (0.57) | NCK1BACE1CYP1A2MEN1KMT2A | |
| SCHEMBL22509757 | 0.77 | NCK1 (0.53) | NCK1BACE1CYP1A2MEN1KMT2A | |
| SCHEMBL22509834 | 0.77 | NCK1 (0.53) | NCK1BACE1CYP1A2MEN1KMT2A | |
| SCHEMBL20377250 | 0.77 | NCK1 (0.53) | NCK1BACE1CYP1A2MEN1KMT2A | |
| SCHEMBL22521412 | 0.77 | BACE1 (0.41) | BACE1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL22521421 | 0.77 | KMT2A (0.50) | CYP1A2MEN1KMT2ARAB9AMAPT | |
| SCHEMBL22509841 | 0.76 | MEN1 (0.60) | NCK1BACE1CYP1A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020205867-A1 | COMPOUNDS TARGETING PRMT5 | ALIGOS THERAPEUTICS, INC. (US) | 2020-10-08 | — | — | WO | disclosed |