Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 18/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 17/20 | 0.37 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.34 |
| ▸ | ADK | P55263 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22521454 | 0.84 | PRMT5 (0.42) | PRMT5WDR77RAPGEF3ADK | |
| SCHEMBL21061719 | 0.84 | PRMT5 (0.42) | PRMT5WDR77RAPGEF3ADK | |
| SCHEMBL29522691 | 0.84 | PRMT5 (0.42) | PRMT5WDR77RAPGEF3ADK | |
| SCHEMBL23430012 | 0.84 | PRMT5 (0.42) | PRMT5WDR77RAPGEF3ADK | |
| SCHEMBL21130306 | 0.83 | PRMT5 (0.39) | PRMT5WDR77RAPGEF3ADK | |
| SCHEMBL22509637 | 0.83 | PRMT5 (0.39) | PRMT5WDR77RAPGEF3ADK | |
| SCHEMBL24595508 | 0.76 | PRMT5 (0.39) | PRMT5WDR77RAPGEF3ADK | |
| SCHEMBL22494884 | 0.74 | PRMT5 (0.46) | PRMT5WDR77RAPGEF3ADK | |
| SCHEMBL22494921 | 0.74 | PRMT5 (0.46) | PRMT5WDR77RAPGEF3ADK | |
| SCHEMBL30002812 | 0.74 | PRMT5 (0.46) | PRMT5WDR77RAPGEF3ADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020205867-A1 | COMPOUNDS TARGETING PRMT5 | ALIGOS THERAPEUTICS, INC. (US) | 2020-10-08 | — | — | WO | disclosed |