Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | PYGL | P06737 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26203896 | 0.89 | PTGER1 (0.39) | TSHRTDP1L3MBTL1LMNATP53 | |
| SCHEMBL29307148 | 0.88 | TSHR (0.37) | TSHRTDP1L3MBTL1LMNATP53 | |
| SCHEMBL22526055 | 0.85 | CYP4F2 (0.41) | NPC1RAB9APPARGPPARA | |
| SCHEMBL11640050 | 0.78 | IGF1R (0.56) | TSHRTP53MEN1KMT2ATRPV1 | |
| SCHEMBL23842320 | 0.78 | PPARG (0.40) | LMNAPPARGPPARAMEN1KMT2A | |
| SCHEMBL25123141 | 0.77 | PPARG (0.38) | PPARGPPARAMEN1KMT2AACACB | |
| SCHEMBL26229267 | 0.77 | MEN1 (0.38) | PPARGPPARAMEN1KMT2AALOX5 | |
| SCHEMBL26206371 | 0.76 | S1PR1 (0.39) | PPARGACACBALOX5S1PR1 | |
| SCHEMBL23845448 | 0.75 | PPARA (0.50) | PPARGPPARA | |
| SCHEMBL23842319 | 0.75 | KEAP1 (0.42) | TSHRPPARGPPARAALOX5S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020206424-A1 | STAT DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2020-10-08 | — | — | WO | disclosed |