Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 5/20 | 0.38 |
| ▸ | HMGCR | P04035 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TARDBP | Q13148 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3817935 | 0.83 | PTPN7 (0.57) | PTPN7HMGCRKMT2AMEN1CYP1A2 | |
| SCHEMBL23945587 | 0.82 | PTPN7 (0.37) | PTPN7HMGCRKMT2AMEN1KDM4E | |
| SCHEMBL22526118 | 0.82 | PAOX (0.43) | PTPN7HMGCRRECQLTDP1ALDH1A1 | |
| SCHEMBL25110937 | 0.82 | PAOX (0.43) | PTPN7HMGCRRECQLTDP1ALDH1A1 | |
| SCHEMBL7626673 | 0.81 | PTPN7 (0.38) | PTPN7HMGCRKMT2AMEN1SOAT1 | |
| SCHEMBL25468189 | 0.80 | PTPN7 (0.40) | PTPN7HMGCR | |
| SCHEMBL24765696 | 0.80 | PTPN7 (0.40) | PTPN7HMGCR | |
| SCHEMBL25110145 | 0.80 | PTPN7 (0.40) | PTPN7HMGCR | |
| SCHEMBL25122683 | 0.79 | PTPN7 (0.35) | PTPN7HMGCRKMT2AMEN1KDM4E | |
| Bicarbonate SCHEMBL4957571 | 0.75 | PTPN7 (0.52) | PTPN7HMGCRKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020206424-A1 | STAT DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2020-10-08 | — | — | WO | disclosed |