SCHEMBL22533153

SCHEMBL22533153

CCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)OCC(N)C(=O)O)OC(=O)CCCCCCCCCCCCC

nearest known ligand 0.75

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
P2RY10 O00398 11/20 0.75
GPR34 Q9UPC5 7/20 0.75
GPR174 Q9BXC1 7/20 0.75
LPAR3 Q9UBY5 4/20 0.71
LPAR1 Q92633 3/20 0.71
ENPP2 Q13822 1/20 0.70
SMN1; SMN2 Q16637 1/20 0.70
FABP3 P05413 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22532171 1.00 P2RY10 (0.75) P2RY10GPR34GPR174LPAR3LPAR1
SCHEMBL21795574 1.00 P2RY10 (0.75) P2RY10GPR34GPR174LPAR3LPAR1
Phosphatidyl Serine SCHEMBL20767229 1.00 P2RY10 (0.75) P2RY10GPR34GPR174LPAR3LPAR1
SCHEMBL22498713 1.00 P2RY10 (0.75) P2RY10GPR34GPR174LPAR3LPAR1
SCHEMBL22531350 1.00 P2RY10 (0.75) P2RY10GPR34GPR174LPAR3LPAR1
Phosphatidyl Serine SCHEMBL24802704 1.00 P2RY10 (0.75) P2RY10GPR34GPR174LPAR3LPAR1
SCHEMBL22532168 1.00 P2RY10 (0.75) P2RY10GPR34GPR174LPAR3LPAR1
SCHEMBL22531357 1.00 P2RY10 (0.75) P2RY10GPR34GPR174LPAR3LPAR1
SCHEMBL22532089 1.00 P2RY10 (0.75) P2RY10GPR34GPR174LPAR3LPAR1
SCHEMBL237694 1.00 P2RY10 (0.75) P2RY10GPR34GPR174LPAR3LPAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12622979-B2 Lipid nanoparticle used for delivering nucleic acid to brain tissue NOF CORPORATION (JP) 2026-05-12 US disclosed
US-20260115316-A1 LIPID NANOPARTICLES FOR DELIVERING NUCLEIC ACID TO SPLENIC TISSUE, AND METHOD FOR DELIVERING NUCLEIC ACID TO SPLENIC TISSUE USING SAME NOF CORPORATION (JP) 2026-04-30 US disclosed
US-20250197852-A1 LIPID NANOPARTICLES USED TO TRANSPORT NUCLEIC ACIDS INTO LYMPHATIC ENDOTHELIUM CELLS NOF CORPORATION (JP) 2025-06-19 US disclosed
EP-4501360-A1 LIPID NANOPARTICLES FOR DELIVERING NUCLEIC ACID TO SPLENIC TISSUE, AND METHOD FOR DELIVERING NUCLEIC ACID TO SPLENIC TISSUE USING SAME NOF Corporation (JP) 2025-02-05 EP disclosed
US-20240408230-A1 LIPID NANOPARTICLE USED FOR DELIVERING NUCLEIC ACID TO BRAIN TISSUE NOF CORPORATION (JP) 2024-12-12 US disclosed
CN-118973614-A Lipid nanoparticles for delivery of nucleic acids to spleen tissue and methods of using the same for delivery of nucleic acids to spleen tissue 日油株式会社 2024-11-15 CN disclosed
EP-4410275-A1 LIPID NANOPARTICLE USED FOR DELIVERING NUCLEIC ACID TO BRAIN TISSUE NOF Corporation (JP) 2024-08-07 EP disclosed
EP-4410276-A1 LIPID NANOPARTICLES USED TO TRANSPORT NUCLEIC ACIDS INTO LYMPHATIC ENDOTHELIUM CELLS NOF Corporation (JP) 2024-08-07 EP disclosed
EP-4395820-A2 NOVEL LIPID NANOPARTICLES FOR DELIVERY OF NUCLEIC ACIDS COMPRISING PHOSPHATIDYLSERINE CureVac SE (DE) 2024-07-10 EP disclosed
CN-118284407-A Lipid nanoparticles for delivery of nucleic acids to brain tissue 日油株式会社 2024-07-02 CN disclosed
CN-118251212-A Lipid nanoparticles for delivery of nucleic acids to lymphatic endothelial cells 日油株式会社 2024-06-25 CN disclosed
CN-117940158-A Novel lipid nanoparticles comprising phosphatidylserine for nucleic acid delivery 库瑞瓦格欧洲公司 2024-04-26 CN disclosed
WO-2023190176-A1 LIPID NANOPARTICLES FOR DELIVERING NUCLEIC ACID TO SPLENIC TISSUE, AND METHOD FOR DELIVERING NUCLEIC ACID TO SPLENIC TISSUE USING SAME 日油株式会社 2023-10-05 WO disclosed
WO-2023054241-A1 LIPID NANOPARTICLE USED FOR DELIVERING NUCLEIC ACID TO BRAIN TISSUE 日油株式会社 2023-04-06 WO disclosed
WO-2023054242-A1 LIPID NANOPARTICLES USED TO TRANSPORT NUCLEIC ACIDS INTO LYMPHATIC ENDOTHELIUM CELLS 日油株式会社 2023-04-06 WO disclosed
WO-2023031392-A2 NOVEL LIPID NANOPARTICLES FOR DELIVERY OF NUCLEIC ACIDS COMPRISING PHOSPHATIDYLSERINE CureVac SE (DE) 2023-03-09 WO disclosed
US-20220193108-A1 Immunotherapeutic Nanoparticles And Methods Relating Thereto WAKE FOREST UNIVERSITY HEALTH SCIENCES 2022-06-23 US disclosed
WO-2020210317-A1 IMMUNOTHERAPEUTIC NANOPARTICLES AND METHODS RELATING THERETO WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) 2020-10-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260115316-A1 LIPID NANOPARTICLES FOR DELIVERING NUCLEIC ACID TO SPLENIC TISSUE, AND METHOD FOR DELIVERING NUCLEIC ACID TO SPLENIC TISSUE USING SAME SREBF1, SREBF2, FABP1 P2RY10 4842/4885GPR34 3787/4885GPR174 3668/4885
US-20250197852-A1 LIPID NANOPARTICLES USED TO TRANSPORT NUCLEIC ACIDS INTO LYMPHATIC ENDOTHELIUM CELLS LIPG, NPC1L1, FLT1 P2RY10 4656/4885GPR34 3551/4885GPR174 1561/4885
US-20240408230-A1 LIPID NANOPARTICLE USED FOR DELIVERING NUCLEIC ACID TO BRAIN TISSUE PHOSPHO1, FABP7, SGMS1 P2RY10 4712/4885GPR34 4397/4885GPR174 2791/4885
US-12622979-B2 Lipid nanoparticle used for delivering nucleic acid to brain tissue FABP7, SREBF1, SREBF2 P2RY10 4869/4885GPR34 3763/4885GPR174 4063/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.