Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 19/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 19/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26346679 | 0.92 | OPRL1 (0.40) | OPRL1OPRM1 | |
| SCHEMBL26343235 | 0.76 | OPRL1 (0.45) | OPRL1OPRM1 | |
| SCHEMBL21766362 | 0.74 | OPRL1 (0.56) | OPRL1OPRM1 | |
| SCHEMBL20866632 | 0.70 | OPRM1 (0.49) | OPRL1OPRM1 | |
| SCHEMBL2780290 | 0.70 | OPRL1 (0.59) | OPRL1OPRM1 | |
| SCHEMBL19145436 | 0.69 | OPRL1 (0.54) | OPRL1OPRM1 | |
| Hydrochloric Acid SCHEMBL2378571 | 0.69 | OPRL1 (0.58) | OPRL1OPRM1 | |
| SCHEMBL4051249 | 0.68 | OPRL1 (0.63) | OPRL1OPRM1 | |
| SCHEMBL2782285 | 0.68 | OPRL1 (0.67) | OPRL1OPRM1 | |
| SCHEMBL3144048 | 0.68 | OPRL1 (0.62) | OPRL1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3722284-A1 | 3-((HETERO-)ARYL)-8-AMINO-2-OXO-1,3-DIAZA-SPIRO-[4.5]-DECANE DERIVATIVES | Grünenthal GmbH (DE) | 2020-10-14 | — | — | EP | disclosed |