Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.63 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.63 |
| ▸ | HTR2C | P28335 | 10/20 | 0.63 |
| ▸ | HTR1A | P08908 | 3/20 | 0.58 |
| ▸ | HTR6 | P50406 | 3/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12180448 | 0.88 | ACHE (0.54) | SLC6A2SLC6A4SLC6A3HTR2CHTR1A | |
| SCHEMBL1266168 | 0.87 | HTR2C (0.63) | SLC6A2SLC6A4SLC6A3HTR2CHTR1A | |
| SCHEMBL2707057 | 0.83 | HTR2C (0.63) | SLC6A2SLC6A4SLC6A3HTR2CHTR1A | |
| SCHEMBL6709469 | 0.83 | SLC6A2 (0.59) | SLC6A2SLC6A4SLC6A3HTR2CHTR1A | |
| SCHEMBL23712339 | 0.82 | HTR2C (0.61) | SLC6A2SLC6A4SLC6A3HTR2CHTR1A | |
| SCHEMBL6036481 | 0.82 | HTR2C (0.66) | SLC6A2SLC6A4SLC6A3HTR2CHTR1A | |
| SCHEMBL5669793 | 0.82 | HTR2C (0.61) | SLC6A2SLC6A4SLC6A3HTR2CHTR1A | |
| SCHEMBL17376358 | 0.82 | HTR2C (0.61) | SLC6A2SLC6A4SLC6A3HTR2CHTR1A | |
| Hydrochloric Acid SCHEMBL4891726 | 0.81 | HTR2C (0.67) | SLC6A2SLC6A4SLC6A3HTR2CHTR1A | |
| SCHEMBL6709455 | 0.81 | HTR2C (0.59) | SLC6A2SLC6A4SLC6A3HTR2CHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4289835-A1 | CDK INHIBITOR | Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. (CN) | 2023-12-13 | — | — | EP | disclosed |
| WO-2021254389-A1 | PYRAZOLO[3,4-D]PYRIMIDINE-3-KETONE DERIVATIVE AS WEE-1 INHIBITOR | 微境生物医药科技(上海)有限公司 | 2021-12-23 | — | — | WO | disclosed |
| WO-2020210377-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | NUVATION BIO INC. (US) | 2020-10-15 | — | — | WO | disclosed |
| WO-2020210383-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | NUVATION BIO INC. (US) | 2020-10-15 | — | — | WO | disclosed |